Evidence map›Paper›PMID 30158921›Full record

ArticleFrontiers in immunology2018

Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma.

Julie Di Cristofaro, Karlin R Karlmark, Sami B Kanaan, Doua F Azzouz, Marina El Haddad, Lucas Hubert, Dominique Farge-Bancel, Brigitte Granel, Jean Robert Harlé, Eric Hachulla and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Julie Di CristofaroAix Marseille Univ, CNRS, EFS, ADES, "Biologie des Groupes Sanguins", Marseille, France.
Karlin R KarlmarkAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.
Sami B KanaanAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.
Doua F AzzouzAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.
Marina El HaddadAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.
Lucas HubertImmunogenetics Laboratory, EFS-Alpes Méditerranée, Marseille, France.
Dominique Farge-BancelUnité de Médecine Interne Maladies Auto-immunes et Pathologie Vasculaire (UF 04) Hôpital Saint Louis, AP-HP, Centre de Référence des Maladies auto-immunes systémiques Rares d'Île-de-France, FAI2R, EA 3518, Institut Universitaire d'Hématologie, Paris, France.
Brigitte GranelUMR-S 1076 Endothélium, Pathologies Vasculaires et Cibles Thérapeutiques - Faculté de Pharmacie, Marseille, France.
Jean Robert HarléAP-HM, Pôle de Médecine Interne, Centre de Compétence PACA Ouest pour la prise en charge des maladies autoimmunes systémiques, Marseille, France.
Eric HachullaService de Médecine Interne, Centre National de Référence de la Sclérodermie Systémique, Hôpital Claude Huriez, Lille, France.
Etienne PardouxAix Marseille Univ, CNRS, Centrale Marseille, I2M, Marseille, France.
Jean RoudierAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.
Christophe PicardAix Marseille Univ, CNRS, EFS, ADES, "Biologie des Groupes Sanguins", Marseille, France.
Nathalie C LambertAix Marseille Univ, INSERM, Autoimmune Arthritis (AA), Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with scleroderma (SSc) maintain significantly higher quantities of persisting fetal microchimerism (FMc) from complete or incomplete pregnancies in their peripheral blood compared to healthy women. The non-classical class-I human leukocyte antigen (HLA) molecule HLA-G plays a pivotal role for the implantation and maintenance of pregnancy and has often been investigated in offspring from women with pregnancy complications. However data show that maternal

Indexed as

ChimerismGene ExpressionAdultAgedAllelesAutoantibodiesCase-Control StudiesFemaleFetal DevelopmentGene FrequencyGenotypeHaplotypesHLA-G AntigensHumansMaleMiddle AgedAutoantibodiesHLA-G AntigensUntranslated Regionsfetalhuman leukocyte antigen-Gmicrochimerismpregnancysclerodermasystemic sclerosis

Identifiers

PMID30158921
PMCPMC6104483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.