Evidence map›Paper›PMID 30158912›Full record

ArticleFrontiers in microbiology2018

Gut Microbiota and Relevant Metabolites Analysis in Alcohol Dependent Mice.

Guanhao Wang, Qing Liu, Liang Guo, Haijuan Zeng, Chengchao Ding, Wentong Zhang, Dongpo Xu, Xiang Wang, Jingxuan Qiu, Qingli Dong and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  15. Cyclic Nucleotide Phosphodiesterases in Alcohol Use Disorders: Involving Gut Microbiota.The international journal of neuropsychopharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guanhao WangSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Qing LiuSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Liang GuoSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Haijuan ZengSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Chengchao DingSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Wentong ZhangSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Dongpo XuSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Xiang WangSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Jingxuan QiuSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Qingli DongSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Ziquan FanThermo Fisher Scientific, Shanghai, China.
Qi ZhangSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Jing PanSchool of Medical Instruments and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol abuse is a major public health crisis. Relative evidences supported that the gut microbiota (GM) played an important role in central nervous system (CNS) function, and the composition of them had changed after alcohol drinking. We sought to explore the changes of GM in alcohol dependence. In our study, the GM of mice with alcohol administration was detected through analyzed 16S rRNA gene sequencing and the fecal metabolites were analyzed by LC-MS. The microbial diversity was significantly higher in the alcohol administration group, the abundance of phylum

Indexed as

16S rRNA gene sequencingalcohol additiongut microbiotaLC-MStissue damage

Identifiers

PMID30158912
PMCPMC6104187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.