Evidence map›Paper›PMID 30158874›Full record

ArticleFrontiers in physiology2018

Hyper-Oxygenation Attenuates the Rapid Vasodilatory Response to Muscle Contraction and Compression.

Alessandro Messere, Michael Tschakovsky, Stefano Seddone, Gabriella Lulli, Walter Franco, Daniela Maffiodo, Carlo Ferraresi, Silvestro Roatta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Alessandro MessereDepartment of Neuroscience, University of Turin, Turin, Italy.
Michael TschakovskyHuman Vascular Control Lab, School of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Stefano SeddoneDepartment of Neuroscience, University of Turin, Turin, Italy.
Gabriella LulliDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Walter FrancoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Daniela MaffiodoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Carlo FerraresiDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Silvestro RoattaDepartment of Neuroscience, University of Turin, Turin, Italy.
Polytechnic University of Turin · ITUniversity of Turin · ITQueen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A single muscle compression (MC) with accompanying hyperemia and hyper-oxygenation results in attenuation of a subsequent MC hyperemia, as long as the subsequent MC takes place when muscle oxygenation is still elevated. Whether this is due to the hyper-oxygenation, or compression-induced de-activation of mechano-sensitive structures is unclear. We hypothesized that increased oxygenation and not de-activation of mechano-sensitive structures was responsible for this attenuation and that both compression and contraction-induced hyperemia attenuate the hyperemic response to a subsequent muscle contraction, and vice-versa.

Indexed as

hyperemiamuscle blood flowmuscle compressionmuscle contractiontissue oxygenation

Identifiers

PMID30158874
PMCPMC6104350
OpenAlexW2887651413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.