ArticleFrontiers in human neuroscience2018
Differential Effects of Intranasal Vasopressin on the Processing of Adult and Infant Cues: An ERP Study.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Intranasal vasopressin, but not oxytocin, decreases ethanol intake in socially housed mice.Psychopharmacology · 2026Article
- Vasopressin as Possible Treatment Option in Autism Spectrum Disorder.Biomedicines · 2023Review
- Arginine Vasopressin, Synaptic Plasticity, and Brain Networks.Current neuropharmacology · 2022Review
- Vasopressin in the Amelioration of Social Functioning in Autism Spectrum Disorder.Journal of clinical medicine · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arginine vasopressin (AVP) is a powerful regulator of various social behaviors across many species. However, seemingly contradictory effects of AVP have been found in both animal and human studies, e.g., promoting aggression on one hand and facilitating social bonding on the other hand. Therefore, we hypothesize that the role of AVP in social behaviors is context-dependent. To this end, we examined the modulatory effect of AVP on male's behavioral and neural responses to infant and adult cues. After intranasal and double-blind treatment of AVP or placebo, male participants were asked to rate their subjective approaching willingness to infant and adult faces in specific contexts informed by cue words while EEG recording. Our results showed that AVP treatment increased approaching ratings to neutral and positive other-gender adult faces compared to emotional matched same-gender adult faces, and to negative girl faces compared to negative boy faces. Furthermore, compared to placebo treatment, AVP treatment induced larger N1 amplitudes to neutral cues associated with both adults and infants, whereas AVP treatment only sustained pronounced late positive potential amplitudes to neutral cues of infants but not adults. Those findings implicate differential roles of AVP in the processing of adult- and infant-related cues and thus lend support to the context-dependent account.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.