Evidence map›Paper›PMID 30158806›Full record

ReviewJournal of human reproductive sciences

Urinary Versus Recombinant Gonadotropins for Ovarian Stimulation in Women Undergoing Treatment with Assisted Reproductive Technology.

Ameet Patki, Himanshu Bavishi, Chandravati Kumari, Jayarani Kamraj, M Venugopal, K U Kunjimoideen, Poornima Nadkarni, Samundi Sankari, Sunil Chaudhary, M J Sangeeta and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hormonal treatment for men with Non-obstructive Azoospermia: too many rationales, too little data.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ameet PatkiDepartment of Reproductive Endocrinology, Fertility Associates, Mumbai, Maharashtra, India.
Himanshu BavishiDepartment of Reproductive Endocrinology, Bavishi Fertility Institute, Ahmedabad, Gujarat, India.
Chandravati KumariKrishna Medical Center, Lucknow, Uttar Pradesh, India.
Jayarani KamrajAakash Fertility Centre and Hospital, Chennai, Tamil Nadu, India.
M VenugopalARMC IVF, Thrissur, Kerala, India.
K U KunjimoideenARMC IVF, Kozhikode, Kerala, India.
Poornima NadkarniDepartment of IVF, Nadkarni Hospital and 21 Century Hospitals, Surat, Gujarat, India.
Samundi SankariSrushti Fertility Centre, Chennai, Tamil Nadu, India.
Sunil ChaudharyJammu Centre for Human Reproduction, Jammu, Jammu and Kashmir, India.
M J SangeetaCaree Fertility Centre, Bengaluru, Karnataka, India.
C S ManjunathMathrutva Fertility Center, Bengaluru, Karnataka, India.
Pratap KumarDepartment of Obstetrics and Gynaecology, Kasturba Medical College, Manipal, Karnataka, India.
Bloom Fertility Centre · INKasturba Medical College, Manipal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, about 10%-15% couples are affected by infertility, with major role being played by the couple's lifestyle. Several gonadotropin preparations (urinary, purified urinary, recombinant, and biosimilars) are available for use. Purified urinary formulations offer numerous advantages over their predecessor, including lesser injection dose required, ability to be administered subcutaneously, less batch-to-batch variability, better efficacy, ability to individualize protocols as per patient's need, better control of developing follicles, less risk of multiple pregnancies, and hyperstimulation. Published results of Cochrane reviews and meta-analysis show no difference in efficacy or safety between urinary and recombinant gonadotropins. In the absence of any significant difference, cost plays an important role in deciding choice of gonadotropins. In this article, we have reviewed the results of comparative clinical trials, Cochrane analysis, and meta-analysis to derive consensus statements regarding efficacy, safety, and cost implications of urinary versus recombinant gonadotropin preparations.

Indexed as

Ovulationrecombinanturinary gonadotropins

Identifiers

PMID30158806
PMCPMC6094533
OpenAlexW2887048606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.