Evidence map›Paper›PMID 30158747›Full record

ArticleIndian journal of nephrology

Effects of Citrate Acid Concentrate on Hemodialysis Adequacy, Reuse, and Quality of Life: A Prospective Randomized Crossover Trial.

S P Nagaraju, S Kosuru, R Parthasarathy, A S Mareddy, R P Attur, D Rangaswamy, S Prasad, S Kaza, S Shenoy, K Saraf and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

S P NagarajuDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
S KosuruDepartment of Nephrology, Mahatma Gandhi Hospitals, Narasaraopet, Andhra Pradesh, India.
R ParthasarathyDepartment of Nephrology, Madras Mission Hospital, Chennai, Tamil Nadu, India.
A S MareddyDepartment of Nephrology, Guntur City Hospitals, Guntur, Andhra Pradesh, India.
R P AtturDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
D RangaswamyDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
S PrasadDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
S KazaDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
S ShenoyDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
K SarafDepartment of Nephrology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
S L K LaxminarayanaDepartment of Pathology, Kasturba Medical College, Manipal University, Udupi, Karnataka, India.
U V MatetiDepartment of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Nitte University, Mangalore, Karnataka, India.
V GuddattuDepartment of Statistics, Prasanna School of Public Health, Manipal University, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a randomized crossover trial to identify whether the use of citrate dialysate (CD) for bicarbonate hemodialysis is beneficial compared to regular acetate dialysate (AD) in terms of adequacy, reuse, and quality of life. Thirty-two stable end-stage renal disease patients on twice-weekly maintenance hemodialysis were randomly assigned to CD or AD fluid in a single-blinded randomized prospective crossover trial of 1-year duration. The primary outcomes studied were the impact of CD in comparison with AD on hemodialysis adequacy, reuse of dialyzer, and quality of life. Secondary outcomes studied were the effect on intradialytic hypotension, acidosis correction, and episodes of symptomatic hypocalcemia. A total number of 28 patients underwent a total of 1456 sessions of hemodialysis with CD over 6 months and 1456 sessions with AD over 6 months. There was a significant increase in dialyzer reuse with the use of CD (

Indexed as

Citrate dialysatedialysis adequacydialyzer reusequality of life

Identifiers

PMID30158747
PMCPMC6094840

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.