ArticleNature genetics2018
COSMIC-3D provides structural perspectives on cancer genetics for drug discovery.
Article in Nature genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Genome-Wide Characterisation of Somatic Mutations Across COSMIC Cancer Cell Lines Enables Gene-Centric Experimental Model Selection.International journal of molecular sciences · 2026Article
- Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D.Nature communications · 2026Article
- BEstimate: a computational tool for the design and interpretation of CRISPR base editing experiments.Genome biology · 2026Article
- Prevalence and impact of molecular variation in the three-prime repair exonuclease 1 TREX1 and its implications for oncology.Human genomics · 2025Article
- Translating pharmacogenomic sequencing data into drug response predictions-How to interpret variants of unknown significance.British journal of clinical pharmacology · 2025Review
- Mut-Map: Comprehensive Computational Pipeline for Structural Mapping and Analysis of Cancer-Associated Mutations.Briefings in bioinformatics · 2024Article
- Review
- COSMIC: a curated database of somatic variants and clinical data for cancer.Nucleic acids research · 2024Article
- Delineation of functionally essential protein regions for 242 neurodevelopmental genes.Brain : a journal of neurology · 2023Article
- Central resources of variant discovery and annotation and its role in precision medicine.Asian biomedicine : research, reviews and news · 2022Review
- Article
- Venus: Elucidating the Impact of Amino Acid Variants on Protein Function Beyond Structure Destabilisation.Journal of molecular biology · 2022Article
- DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition.Cancer discovery · 2022Article
- Identification of NADFrontiers in genetics · 2022Article
- Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy.Cancer cell · 2021Article
- COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets.Briefings in bioinformatics · 2021Article
- Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology.NPJ precision oncology · 2021Article
- MISCAST: MIssense variant to protein StruCture Analysis web SuiTe.Nucleic acids research · 2020Article
- Online informatics resources to facilitate cancer target and chemical probe discovery.RSC medicinal chemistry · 2020Review
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.