ArticleScientific reports2018
Seroprevalence of Maternal and Cord Antibodies Specific for Diphtheria, Tetanus, Pertussis, Measles, Mumps and Rubella in Shunyi, Beijing.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Seroprevalence of IgG antibodies against pertussis toxin in the Chinese population: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2024Pooled it
- Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT.BMC infectious diseases · 2023Pooled it
- Pooled it
- Breastfeeding and the Risk of Infant Illness in Asia: A Review.International journal of environmental research and public health · 2019Pooled it
- Parent-driven transmission, off-label SMZ-TMP, and severe pertussis prediction in infants under 2 months: a real-world observational cohort of 527 cases.Frontiers in pediatrics · 2026Article
- Persistence of Antibodies against Measles, Mumps, and Rubella after the Two-Dose MMR Vaccination: A 7-Year Follow-Up Study.Vaccines · 2024Article
- COVID-19 booster enhances IgG mediated viral neutralization by human milkFrontiers in nutrition · 2024Article
- Mumps serological surveillance following 10 years of a one-dose mumps-containing-vaccine policy in Fujian Province, China.Human vaccines & immunotherapeutics · 2022Article
- Seroepidemiology of pertussis and diphtheria among healthy adults in Shaanxi Province, northwest China: A large - scale cross-sectional study.Human vaccines & immunotherapeutics · 2022Article
- Article
- Successful seroconversion against diphtheria and tetanus induced through maternal vaccination in a region of Colombia.Clinical and experimental vaccine research · 2022Article
- Serological Responses to Influenza Vaccination during Pregnancy.Microorganisms · 2021Review
- One single-center serological survey on measles, rubella and mumps antibody levels of people in Youyang, China.Human vaccines & immunotherapeutics · 2021Article
- Decline of serologic immunity to diphtheria, tetanus and pertussis with age suggested a full life vaccination in mainland China.Human vaccines & immunotherapeutics · 2021Article
- Vertically Transferred Immunity in Neonates: Mothers, Mechanisms and Mediators.Frontiers in immunology · 2020Review
- The maternal antibody against diphtheria, tetanus and pertussis showed distinct regional difference in China.BMC pediatrics · 2019Article
- Antibodies against measles and rubella virus among different age groups in Thailand: A population-based serological survey.PloS one · 2019Article
- Rubella seroprevalence among pregnant women in Beijing, China.BMC infectious diseases · 2018Article
- [Clinical features and epidemiological significance of pertussis in infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsArticle
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Maternal antibodies contribute to the protection of young infants from infectious diseases during the early life. However, vaccinations for women of child-bearing age are not routine in China. Therefore, we investigated the level of protective immunity against vaccine preventable diseases in pregnant women and newborns in China. A total of 194 paired maternal and cord blood samples were collected in Beijing from 2016 to 2017. Antibodies specific for the antigens covered by diphtheria-tetanus-pertussis (DTP) and measles-mumps-rubella (MMR) vaccine were determined by ELISA (Euroimmun, Lübeck, Germany). The cut off value of ≥0.1 IU/ml (anti-diphtheria), >0.1 IU/ml (anti-tetanus), >40 IU/ml (anti-pertussis toxin), ≥200 IU/l (anti-measles), ≥45 RU/ml (anti-mumps) and ≥10 IU/ml (anti-rubella) were used to assess the percentage of newborns with protective IgG concentrations, respectively. The results revealed that 61.3%, 73.2%, 97.4%, 30.4%, 65.5% and 17.0% of newborns had no protection against diphtheria, tetanus, pertussis, measles, mumps and rubella. Only 1.0% and 23.7% of newborns had protection against all three components of DTP or MMR, respectively. The finding suggested that most of newborns were susceptible to diphtheria, tetanus, pertussis and mumps, almost one-third of this population had no immune protection against measles, and about one-sixth of them were under threat of rubella infection. These data supported the immunization program for DTP and MMR vaccine in women at child-bearing age.
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