Evidence map›Paper›PMID 30158678›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2018

Impact of respiratory viruses in the neonatal intensive care unit.

Jessica E Shui, Maria Messina, Alexandra C Hill-Ricciuti, Philip Maykowski, Tina Leone, Rakesh Sahni, Joseph R Isler, Lisa Saiman

Abstract readObservational Study
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jessica E ShuiDivision of Neonatology, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Maria MessinaDivision of Infectious Diseases, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Alexandra C Hill-RicciutiDivision of Infectious Diseases, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-2411-2712
Philip MaykowskiDivision of Infectious Diseases, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Tina LeoneDivision of Neonatology, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Rakesh SahniDivision of Neonatology, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Joseph R IslerDivision of Neonatology, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Lisa SaimanDivision of Infectious Diseases, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA. Ls5@cumc.columbia.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the epidemiology and clinical impact of respiratory viruses in a neonatal intensive care unit (NICU). STUDY

designWe conducted a retrospective observational study of infants with respiratory viruses detected by multiplex reverse-transcriptase PCR from May 2012 to May 2017. The proportion of symptomatic vs. asymptomatic infants and associated morbidity were assessed. The association of infection prevention and control (IP&C) strategies and transmission was ascertained.

resultsRespiratory viruses were detected in 83 infants representing 86 unique episodes during which infants remained asymptomatic in 15 (17%). Of the 71 symptomatic episodes, only 45% were associated with increased respiratory and/or nutritional support. Rhinovirus/enteroviruses were most common (69%) and involved nine of 12 transmission events. IP&C strategies including restricting visitors <12 years of age and screening exposed infants were associated with decreased transmission rates.

conclusionsNICU patients can be asymptomatic carriers of respiratory viruses. Identification of such infants is important to prevent transmission in the NICU.

Indexed as

Intensive Care Units, NeonatalFemaleHumansInfantInfant, NewbornInfection ControlMaleMultiplex Polymerase Chain ReactionRespiratory Tract InfectionsRetrospective StudiesViruses

Identifiers

PMID30158678
PMCPMC7100236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.