Evidence map›Paper›PMID 30158677›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Implementation of the sepsis risk score for chorioamnionitis-exposed newborns.

Ladawna L Gievers, Jennifer Sedler, Carrie A Phillipi, Dmitry Dukhovny, Jonah Geddes, Peter Graven, Benjamin Chan, Sheevaun Khaki

Abstract readEvaluation Study
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ladawna L GieversDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA. gievers@ohsu.edu.ORCID 0000-0002-7634-5887
Jennifer SedlerSchool of Medicine, University of Arizona, Tucson, AZ, USA.
Carrie A PhillipiDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA.
Dmitry DukhovnyDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA.
Jonah GeddesCenter for Health Systems Effectiveness, Oregon Health and Science University, Portland, OR, USA.
Peter GravenCenter for Health Systems Effectiveness, Oregon Health and Science University, Portland, OR, USA.
Benjamin ChanSchool of Public Health, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0002-6644-5358
Sheevaun KhakiDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo prevent early onset sepsis (EOS), ~10% of neonates receive antibiotics based on CDC recommendations regarding chorioamnionitis exposure. A sepsis risk score (SRS) predicts EOS and spares unnecessary evaluation and treatment. LOCAL PROBLEM: Chorioamnionitis-exposed neonates utilize significant resources.

methodsAn SRS algorithm was implemented to decrease resource utilization in chorioamnionitis-exposed neonates ≥35 weeks'. Outcome measures included antibiotic exposure, time in NICU, laboratory evaluations, and length of stay (LOS). Balancing measures were missed cases of EOS and readmissions. Data were assessed using run charts.

interventionsPlan-Do-Study-Act cycles were utilized to process map, implement and reinforce the algorithm.

resultsA number of 356 patients met inclusion criteria. After algorithm implementation, antibiotic exposure reduced from 95 to 9%, laboratory evaluation from 96 to 22%, NICU observation from 73 to 10%. LOS remained unchanged. No missed cases of EOS, nor sepsis readmissions.

conclusionsAlgorithm implementation decreased antibiotic and resource utilization without missing cases of EOS.

Indexed as

Decision Support TechniquesAdultAlgorithmsAnti-Bacterial AgentsAntibiotic ProphylaxisChorioamnionitisFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalLength of StayMaleNeonatal SepsisPractice Guidelines as TopicPredictive Value of TestsAnti-Bacterial Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.