Evidence map›Paper›PMID 30158583›Full record

ArticleScientific reports2018

Systemic Injection of Substance P Promotes Murine Calvarial Repair Through Mobilizing Endogenous Mesenchymal Stem Cells.

Yueling Zhang, Shu An, Jin Hao, Feng Tian, Xinyi Fang, Jun Wang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Bioactive materials forBioactive materials · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yueling ZhangState Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Shu AnState Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Jin HaoHarvard School of Dental Medicine, Harvard University, Boston, MA, 02115, USA.
Feng TianF.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Xinyi FangState Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
Jun WangState Key Laboratory of Oral Diseases, Department of Orthodontics, West China School of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. wangjunv@scu.edu.cn.ORCID 0000-0001-9296-0241
Sichuan University · CNBoston Children's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Craniofacial defect is a critical problem in dental clinic, which has a tremendous impact on patients' quality of life. Mesenchymal stem cell-based therapy has emerged as a promising approach for tissue defect repair. However, reduced survival after mesenchymal stem cells (MSCs) transplantation remains as a major problem in this area, which hampers the outcome of regeneration. Recently, the mechanism to mobilize endogenous MSCs for tissue regeneration has received increasing attentions, as it does not require exogenous cell transplantation. The primary goal of this study was to confirm the role of intravenous substance P in mobilizing endogenous CD45

Indexed as

Administration, IntravenousAnimalsCD11b AntigenCell SurvivalCraniofacial DysostosisDisease Models, AnimalFlow CytometryIntegrin beta1Leukocyte Common AntigensMesenchymal Stem CellsMiceNeurotransmitter AgentsSubstance PTreatment OutcomeX-Ray MicrotomographyCD11b AntigenIntegrin beta1Itgam protein, mouseLeukocyte Common AntigensNeurotransmitter AgentsPtprc protein, mouseSubstance P

Identifiers

PMID30158583
PMCPMC6115436
OpenAlexW2888293384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.