Evidence map›Paper›PMID 30158456›Full record

ReviewInternational journal of molecular sciences2018

Delineating Pro-Angiogenic Myeloid Cells in Cancer Therapy.

Benjamin W Johnson, Bhagelu R Achyut, Sadanand Fulzele, Ashis K Mondal, Ravindra Kolhe, Ali S Arbab

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Targeting inflammation as cancer therapy.Journal of hematology & oncology · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Benjamin W JohnsonDepartment of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. bejohnson1@augusta.edu.
Bhagelu R AchyutCancer Animal Models Shared Resource, Winship Cancer Center of Emory University, Atlanta, GA 30322, USA. bhagelu.r.achyut@emory.edu.
Sadanand FulzeleDepartment of Orthopedics, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. sfulzele@augusta.edu.
Ashis K MondalDepartment of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. amondal@augusta.edu.
Ravindra KolheDepartment of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. rkolhe@augusta.edu.ORCID 0000-0002-8283-2403
Ali S ArbabTumor Angiogenesis Laboratory, Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA. aarbab@augusta.edu.

Funding

Understanding Mechanisms of Resistance to Anti-angiogenic TreatmentsR01CA160216 · NCI · HENRY FORD HEALTH SYSTEM · PI ARBAB, ALI SYED · 2012 to 2016
$1.8M
In vivo detection of involvement of endogenous BM progenitor cells in gliomaR01CA172048 · NCI · HENRY FORD HEALTH SYSTEM · PI ARBAB, ALI SYED · 2012 to 2014
$894k
6 · The paper itself

Abstract

Recent evidence suggests that myeloid cells are critical in cancer development and therapy resistance processes. Pharmacological targeting of tumor-associated myeloid cells is an emerging approach among upcoming immune therapies. Surprisingly, myeloid cells are heterogeneous, including a subset of the myeloid cell displaying angiogenic properties in solid tumors. There is an urgent need to delineate angiogenic myeloid cell populations in order to facilitate specific targeting of protumor myeloid cells among heterogeneous pool. This review article is intended to compile all the relevant information in the literature for improved understanding of angiogenic myeloid cells and their role in tumor refractoriness to cancer therapy.

Indexed as

AnimalsAntigens, CDCadherin 5CadherinsHumansImmunotherapyMyeloid CellsNeoplasmsPlatelet Endothelial Cell Adhesion Molecule-1Receptor, TIE-2Vascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2Antigens, CDCadherin 5CadherinsPlatelet Endothelial Cell Adhesion Molecule-1Receptor, TIE-2Vascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2angiogenicantiangiogenicchemotherapyimmunotherapyMDSCmyeloidradiotherapytumor

Identifiers

PMID30158456
PMCPMC6165286

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.