Evidence map›Paper›PMID 30158264›Full record

ArticleBMJ case reports2018

Primary Epstein-Barr virus infection in immunocompetent patients with acute transverse myelitis and a combination of polyradiculitis and anterior horn syndrome as neurological manifestations.

Michiel H F Poorthuis, Suzanne Battjes, J Wendelien Dorigo-Zetsma, Jelle R de Kruijk

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michiel H F PoorthuisDepartment of Neurology, Tergooi, Blaricum, The Netherlands.ORCID http://orcid.org/0000-0001-5198-2823
Suzanne BattjesDepartment of Neurology, Tergooi, Blaricum, The Netherlands.
J Wendelien Dorigo-ZetsmaDepartment of Medical Microbiology, Tergooi, Blaricum, The Netherlands.
Jelle R de KruijkDepartment of Neurology, Tergooi, Blaricum, The Netherlands.
Tergooi · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological manifestations of a primary Epstein-Barr virus (EBV) infection are rare. We describe a case with acute transverse myelitis and another case with a combination of polyradiculitis and anterior horn syndrome as manifestations of a primary EBV infection.The first case is a 50-year-old immunocompetent male diagnosed with acute transverse myelitis, 2 weeks after he was clinically diagnosed with infectious mononucleosis. The second case is an 18-year-old immunocompetent male diagnosed with a combination of polyradiculitis and anterior horn syndrome while he had infectious mononucleosis. The first patient was treated with methylprednisolone. After 1 year, he was able to stop performing clean intermittent self-catheterisation. The second patient completely recovered within 6 weeks without treatment.Primary EBV infection should be considered in immunocompetent patients presenting with acute transverse myelitis and a combination of polyradiculitis and anterior horn syndrome. Antiviral treatment and steroids are controversial, and the prognosis of neurological sequelae is largely unknown.

Indexed as

AdolescentAntiviral AgentsDiagnosis, DifferentialEpstein-Barr Virus InfectionsHumansImmunocompetenceMaleMiddle AgedMotor Neuron DiseaseMyelitis, TransversePolyradiculopathySyndromeTomography, X-Ray ComputedAntiviral Agentsinfection (neurology)infectious diseasesmotor neurone diseaseneurologyspinal cord

Identifiers

PMID30158264
PMCPMC6119397
OpenAlexW2888987159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.