ArticleNeurology2018
Quality of care for ischemic stroke in China vs India: Findings from national clinical registries.
Abstract readComparative StudyMulticenter Study
In one paragraph
Article in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy and safety of mesenchymal stem cell therapies for ischemic stroke: a systematic review and meta-analysis.Stem cells translational medicine · 2024Pooled it
- Factors delaying intravenous thrombolytic therapy in acute ischaemic stroke: a systematic review of the literature.Journal of neurology · 2021Pooled it
- Stem cell-based therapies for ischemic stroke: a systematic review and meta-analysis of clinical trials.Stem cell research & therapy · 2020Pooled it
- HEADS UP 2024: Policy Efforts to Improve Equitable Access to Acute Stroke Care Globally.Journal of the American Heart Association · 2025Review
- Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization-Lancet Neurology Commission.The Lancet. Neurology · 2023Review
- Quality Metrics in Acute Stroke: Time to Own.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Correlation of Quality Metrics of Acute Stroke Care with Clinical Outcomes in an Indian Tertiary-care University Hospital: A Prospective Evidence-based Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- Heterogeneity in the diagnosis and prognosis of ischemic stroke subtypes: 9-year follow-up of 22,000 cases in Chinese adults.International journal of stroke : official journal of the International Stroke Society · 2023Article
- Dysphagia Management and Outcomes in Elderly Stroke Patients with Malnutrition Risk: Results from Chinese Stroke Center Alliance.Clinical interventions in aging · 2022Article
- Prognostic Signature for Human Umbilical Cord Mesenchymal Stem Cell Treatment of Ischemic Cerebral Infarction by Integrated Bioinformatic Analysis.BioMed research international · 2022Article
- Review
- Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke.Frontiers in neurology · 2020Article
- Errors in the Diagnosis of Stroke-Tales of Common Stroke Mimics and Strokes in Hiding.Annals of Indian Academy of NeurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Zixiao LiFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Jeyaraj PandianFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
P N SylajaFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Yilong WangFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Xingquan ZhaoFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Liping LiuFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Chunjuan WangFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Dheeraj KhuranaFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
M V Padma SrivastavaFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Subhash KaulFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Deepti AroraFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Lee H SchwammFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Yongjun WangFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston.
Aneesh B SinghalFrom Vascular Neurology (Z.L., X.Z., Yongjun Wang), Tiantan Clinical Trial and Research Center for Stroke (Yilong Wang, C.W.), and Neuro-Intensive Care Unit (L.L.), Department of Neurology, Beijing TianTan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases (Z.L., Yilong Wang, X.Z., L.L., C.W., Yongjun Wang), Beijing; Department of Neurology (J.P., D.A.), Christian Medical College and Hospital, Ludhiana; Department of Neurology (P.N.S.), SreeChitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India; Center of Stroke (Yilong Wang, X.Z., C.W., Yongjun Wang), Beijing Institute for Brain Disorders, China; Department of Neurology (D.K.), Postgraduate Institute of Medical Education and Research, Chandigarh; Department of Neurology (M.V.P.S.), All-India Institutes of Medical Sciences, New Delhi; Department of Neurology (S.K.), Nizam's Institute of Medical Sciences, Hyderabad, India; and Department of Neurology (L.H.S., A.B.S.), Massachusetts General Hospital, Boston. asinghal@partners.org yongjunwang1962@gmail.com.
Funding
Indo-US Collaborative Stroke Registry and Infrastructure DevelopmentR21NS077442 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SINGHAL, ANEESH B · 2011 to 2013
$475kNINDS NIH HHS R21 NS077442
Abstract
objectiveTo understand stroke risk factors, status of stroke care, and opportunities for improvement as China and India develop national strategies to address their disproportionate and growing burden of stroke.
methodsWe compared stroke risk factors, acute management, adherence to quality performance measures, and clinical outcomes among hospitalized ischemic stroke patients using data from the Indo-US Collaborative Stroke Project (IUCSP) and China National Stroke Registry-II (CNSR-II). The IUCSP included 5 academic stroke centers from different geographic regions (n = 2,066). For comparison, the CNSR-II dataset was restricted to 31 academic hospitals among 219 participating sites from 31 provinces (n = 1,973).
resultsIndian patients were significantly younger, had health insurance less often, and had significantly different risk factors (more often diabetes mellitus, dyslipidemia, and coronary heart disease; less often prior stroke, hypertension, atrial fibrillation, and smoking). Hospitalized Indian patients had greater stroke severity (median NIH Stroke Scale score 10 vs 4), higher rates of IV thrombolysis within 3 hours (7.5% vs 2.4%), greater in-hospital mortality (7.9% vs 1.2%), and worse outcome (3-month modified Rankin Scale score 0-2, 49.3% vs 78.1%) (all
conclusionThese data provide insights into the status of ischemic stroke care in academic urban centers within 2 large Asian countries. Further research is needed to determine whether these patterns are representative of care across the countries, to explain differences in observed severity, and to drive improvements.
Indexed as
Quality of Health CareBrain IschemiaChinaCohort StudiesFemaleHospitalizationHospital MortalityHumansIndiaMaleMiddle AgedRegistriesRisk FactorsSeverity of Illness IndexStroke
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.