Evidence map›Paper›PMID 30158115›Full record

ArticleThe Journal of experimental medicine2018

Cell circuits between B cell progenitors and IL-7

Chris Fistonich, Sandra Zehentmeier, Jeffrey J Bednarski, Runfeng Miao, Hilde Schjerven, Barry P Sleckman, João P Pereira

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. The importance of B cells for osteogenic homeostasis.Cell communication and signaling : CCS · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Impact of sepsis on bone marrow mesenchymal stem cells and its implications for hematopoiesis and immunosuppression.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  7. Increased PRP19 in Hepatocyte Impedes B Cell Function to Promote Hepatocarcinogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. IKAROS Family Transcription Factors in Lymphocyte Differentiation and Function.Advances in experimental medicine and biology · 2024
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chris FistonichDepartment of Immunobiology, Yale University School of Medicine, Yale University, New Haven, CT.
Sandra ZehentmeierDepartment of Immunobiology, Yale University School of Medicine, Yale University, New Haven, CT.
Jeffrey J BednarskiDepartment of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO.
Runfeng MiaoDepartment of Immunobiology, Yale University School of Medicine, Yale University, New Haven, CT.
Hilde SchjervenDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0000-0001-9287-3375
Barry P SleckmanDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-8295-4462
João P PereiraDepartment of Immunobiology, Yale University School of Medicine, Yale University, New Haven, CT Joao.Pereira@yale.edu.ORCID 0000-0002-5694-4938
Yale University · USCornell University · USUniversity of California, San Francisco · USWashington University in St. Louis · US

Funding

INTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007019 · NIAID · YALE UNIVERSITY · PI Carrie L. Lucas, David G. Schatz · 1985 to 2026
$14.4M
THE V(D)J RECOMBINATION REACTION AND ITS IMPACT ON LYMPHOCYTE DEVELOPMENTR01AI047829 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI SLECKMAN, BARRY P · 2000 to 2021
$7.0M
Yale Rheumatic Diseases Research Core CenterP30AR053495 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR · 2007 to 2017
$7.0M
Cellular and molecular analysis of B lymphocyte development and selectionR01AI113040 · NIAID · YALE UNIVERSITY · PI JOAO PEREIRA · 2014 to 2026
$6.0M
NIAID NIH HHS R01 AI047829NIAID NIH HHS R01 AI113040NIAID NIH HHS T32 AI007019NIAMS NIH HHS P30 AR053495
6 · The paper itself

Abstract

B cell progenitors require paracrine signals such as interleukin-7 (IL-7) provided by bone marrow stromal cells for proliferation and survival. Yet, how B cells regulate access to these signals in vivo remains unclear. Here we show that proB and IL-7

Indexed as

AnimalsChemokine CXCL12Interleukin-7Mesenchymal Stem CellsMiceMice, KnockoutPrecursor Cells, B-LymphoidReceptors, Interleukin-7Signal TransductionChemokine CXCL12Cxcl12 protein, mouseInterleukin-7Receptors, Interleukin-7

Identifiers

PMID30158115
PMCPMC6170173
OpenAlexW2889134444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.