Evidence map›Paper›PMID 30157960›Full record

ArticleBMC research notes2018

Clinical epidemiology, risk factors and treatment outcomes of extended-spectrum beta-lactamase producing Enterobacteriaceae bacteremia among children in a Tertiary Care Hospital, Bangkok, Thailand.

Thirapa Nivesvivat, Phunlerd Piyaraj, Sudaluck Thunyaharn, Veerachai Watanaveeradej, Detchvijitr Suwanpakdee

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  9. Antibiotic resistance and ESBL production inBulletin of the National Research Centre · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thirapa NivesvivatDepartment of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand.
Phunlerd PiyarajDepartment of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Sudaluck ThunyaharnFaculty of Medical Technology, Nakhon Ratchasima College, Nakhon Ratchasima, Thailand.
Veerachai WatanaveeradejDepartment of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand.
Detchvijitr SuwanpakdeeDepartment of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand. detchvijitr@gmail.com.
Phramongkutklao College of MedicinePhramongkutklao Hospital · THMaharat Nakhon Ratchasima Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveExtended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae infection is an emerging problem in paediatric populations leading to increased mortality. The purpose of this study was to determine the prevalence, risk factors and clinical outcomes of ESBL-producing Enterobacteriaceae in paediatric blood stream infections (BSIs). A retrospective review of paediatric patients diagnosed with Enterobacteriaceae bacteremia was performed at Phramongkutklao Hospital from 2010 to 2017.

resultsAmong 97 non-duplicated blood isolates, the prevalence of ESBL-producing Enterobacteriaceae was 53.6% (28.9% Escherichia coli and 25.8% Klebsiella spp. isolates). The study indicated that the prevalence of ESBL infection was higher among patients with chronic illness, especially hematologic malignancies, than among patients without underlying disease (P = 0.01). No differences were observed in the prior use of any antibiotics, the use of extended-spectrum cephalosporin, neutropaenia or the presence of an indwelling central venous catheter. Mortality in the ESBL group was significantly higher than that in the non-ESBL group, with observed mortalities of 38.9% and 13.3%, respectively (P < 0.05). In conclusion, BSIs with ESBL-producing Enterobacteriaceae tended to increase infection rates and impact survival rates among paediatric patients.

Indexed as

Anti-Bacterial AgentsBacteremiabeta-LactamasesChildChild, PreschoolEnterobacteriaceaeEnterobacteriaceae InfectionsEscherichia coliHumansInfantInfant, NewbornKlebsiellaRetrospective StudiesRisk FactorsTertiary Care CentersThailandAnti-Bacterial Agentsbeta-LactamasesBacteremiaESBL-producing EnterobacteriaceaePaediatric

Identifiers

PMID30157960
PMCPMC6116370
OpenAlexW2889252613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.