Evidence map›Paper›PMID 30157866›Full record

ReviewJournal of biomedical science2018

H. pylori infection and extra-gastroduodenal diseases.

Feng-Woei Tsay, Ping-I Hsu

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of biomedical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. First regional consensus on the management ofWorld journal of gastroenterology · 2025
    Guideline
  3. Bibliometric analysis ofFrontiers in microbiology · 2025
    Pooled it
  4. Relationship ofCanadian journal of gastroenterology & hepatology · 2023
    Pooled it
  5. Pooled it
  6. Trial
  7. Setting a Standard for Helicobacter pylori Management in Pakistan.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Article
  8. Persistence ofJournal of clinical medicine · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. International journal of molecular sciences · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Relationship betweenFrontiers in cellular and infection microbiology · 2025
    Article
  19. Article
  20. Newer Therapies for RefractoryAntibiotics (Basel, Switzerland) · 2024
    Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Feng-Woei TsayDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital and National Yang-Ming University, 386 Ta Chung 1st Road, Kaohsiung, 813, Taiwan, Republic of China.
Ping-I HsuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital and National Yang-Ming University, 386 Ta Chung 1st Road, Kaohsiung, 813, Taiwan, Republic of China. williamhsup@yahoo.com.tw.
Cheng Shiu University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection is the principal cause of peptic ulcer disease, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma. Recent studies have shown that it may interfere with many biological processes and determine or influence the occurrence of many diseases outside the stomach. Currently, the role of H. pylori in idiopathic thrombocytopenic purpura and iron deficiency anemia is well documented. Emerging evidence suggests that it may also contribute to vitamin B12 deficiency, insulin resistance, metabolic syndrome, diabetes mellitus and non-alcoholic liver disease. Additionally, it may increase the risk of acute coronary syndrome, cerebrovascular disease, neurodegenerative disease and other miscellaneous disorders. Different pathogenic mechanisms have been hypothesized, including the occurrence of molecular mimicry and the induction of a low-grade inflammation. This review summarizes the results of the most relevant studies on the extra-gastroduodenal manifestations of H. pylori infection.

Indexed as

Helicobacter InfectionsHelicobacter pyloriHumansHelicobacter pyloriIdiopathic thrombocytopenic purpura and vitamin B12 deficiencyIron deficiency anemia

Identifiers

PMID30157866
PMCPMC6114542
OpenAlexW2889463706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.