Evidence map›Paper›PMID 30157858›Full record

ArticleEnvironmental health : a global access science source2018

Environmental pollution and social factors as contributors to preterm birth in Fresno County.

Amy M Padula, Hongtai Huang, Rebecca J Baer, Laura M August, Marta M Jankowska, Laura L Jellife-Pawlowski, Marina Sirota, Tracey J Woodruff

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Evidence for Maternal Autoantibodies in the Pathogenesis of Preterm Birth.medRxiv : the preprint server for health sciences · 2025
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  15. Long-term impact of ambient air pollution on preterm birth in Xuzhou, China: a time series study.Environmental science and pollution research international · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amy M PadulaDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, 550 16th Street, Mail Stop 0132, San Francisco, CA, 94143, USA. Amy.Padula@ucsf.edu.ORCID 0000-0003-1435-4814
Hongtai HuangDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, 550 16th Street, Mail Stop 0132, San Francisco, CA, 94143, USA.
Rebecca J BaerDepartment of Pediatrics, University of California, San Diego, USA.
Laura M AugustOffice of Environmental Health Hazard Assessment, California Environmental Protection Agency, Sacramento, USA.
Marta M JankowskaCalit2/Qualcomm Institute, University of California, San Diego, USA.
Laura L Jellife-PawlowskiDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Marina SirotaDepartment of Pediatrics, University of California, San Francisco, USA.
Tracey J WoodruffDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, 550 16th Street, Mail Stop 0132, San Francisco, CA, 94143, USA.

Funding

The UCSF Pregnancy Exposures to Environmental Chemicals (PEEC) Children's CenterP01ES022841 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, TRACEY J. · 2013 to 2018
$3.9M
Traffic-related Air Pollution, Social Factors and Adverse Birth OutcomesR00ES021470 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PADULA, AMY MICHELLE · 2016 to 2018
$746k
Elucidating the Role of the Genetic and Environmental Determinants of Preterm Birth Using Integrative Computational ApproachesK01LM012381 · NLM · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SIROTA, MARINA · 2016 to 2018
$531k
Environmental, Social and Biological Factors and Disparities in Preterm BirthR03ES028368 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PADULA, AMY MICHELLE · 2018 to 2019
$174k
Mark and Lynn Benioff UCSF7027075NIEHS NIH HHS P01 ES022841NIEHS NIH HHS R00 ES021470NIEHS NIH HHS R00ES021470NIEHS NIH HHS R03 ES028368NLM NIH HHS K01 LM012381U.S. National Library of Medicine (US) K01LM012381
6 · The paper itself

Abstract

backgroundEnvironmental pollution exposure during pregnancy has been identified as a risk factor for preterm birth. Most studies have evaluated exposures individually and in limited study populations.

methodsWe examined the associations between several environmental exposures, both individually and cumulatively, and risk of preterm birth in Fresno County, California. We also evaluated early (< 34 weeks) and spontaneous preterm birth. We used the Communities Environmental Health Screening Tool and linked hospital discharge records by census tract from 2009 to 2012. The environmental factors included air pollution, drinking water contaminants, pesticides, hazardous waste, traffic exposure and others. Social factors, including area-level socioeconomic status (SES) and race/ethnicity were also evaluated as potential modifiers of the relationship between pollution and preterm birth.

resultsIn our study of 53,843 births, risk of preterm birth was associated with higher exposure to cumulative pollution scores and drinking water contaminants. Risk of preterm birth was twice as likely for those exposed to high versus low levels of pollution. An exposure-response relationship was observed across the quintiles of the pollution burden score. The associations were stronger among early preterm births in areas of low SES.

conclusionsIn Fresno County, we found multiple pollution exposures associated with increased risk for preterm birth, with higher associations among the most disadvantaged. This supports other evidence finding environmental exposures are important risk factors for preterm birth, and furthermore the burden is higher in areas of low SES. This data supports efforts to reduce the environmental burden on pregnant women.

Indexed as

Socioeconomic FactorsAdolescentAdultCaliforniaEnvironmental ExposureEnvironmental PollutantsEnvironmental PollutionFemaleHumansPregnancyPregnancy OutcomePremature BirthPrevalenceRisk FactorsYoung AdultEnvironmental PollutantsEnvironmental exposurePollutionPrematurityPreterm birthSocial factors

Identifiers

PMID30157858
PMCPMC6114053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.