ArticleBMC genomics2018
Transcriptome dynamics associated with resistance and susceptibility against fusarium head blight in four wheat genotypes.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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55 citing papers in PubMed, 146 citations in OpenAlex.
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- Changes in Serbian Yellow Rust Races Reveal Genotype-Specific Responses of Yield and Quality-Related Traits in Commercial Winter Wheat.Microorganisms · 2026Article
- Transcriptomics and Metabolomics Reveal the Antagonistic Mechanism ofMicroorganisms · 2026Article
- Transcriptional Response of Durum Wheat During Interaction withInternational journal of molecular sciences · 2026Article
- Enhancing genomic prediction of wheat resistance to fusarium head blight through integration of passive resistance traits.Frontiers in plant science · 2026Article
- Comparative transcriptomes reveal insights into different host responses associated with Fusarium head blight resistance in wheat.BMC plant biology · 2025Article
- GWAS analysis of Fusarium head blight resistance in a Nordic-Baltic spring wheat panel.Frontiers in plant science · 2025Article
- A conserved fungal Knr4/Smi1 protein is crucial for maintaining cell wall stress tolerance and host plant pathogenesis.PLoS pathogens · 2025Article
- Transcriptomic analysis of two Chinese wheat landraces with contrasting Fusarium head blight resistance reveals miRNA-mediated defense mechanisms.Frontiers in plant science · 2025Article
- Genetic mapping of deoxynivalenol and fusarium damaged kernel resistance in an adapted durum wheat population.BMC plant biology · 2024Article
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- A recent shift in theFrontiers in plant science · 2024Article
- Transcriptional Profiling Reveals the Wheat Defences against Fusarium Head Blight Disease Regulated by a NAC Transcription Factor.Plants (Basel, Switzerland) · 2023Article
- Untargeted Metabolomics Reveals a Multi-Faceted Resistance Response to Fusarium Head Blight Mediated by theCells · 2023Article
- Transcriptome Dynamic Analysis Reveals New Candidate Genes Associated with Resistance to Fusarium Head Blight in Two Chinese Contrasting Wheat Genotypes.International journal of molecular sciences · 2023Article
- Dual RNA-sequencing of Fusarium head blight resistance in winter wheat.Frontiers in plant science · 2023Article
- Genome-wide association analysis of type II resistance to Fusarium head blight in common wheat.PeerJ · 2023Article
- Differential Expression Feature Extraction (DEFE): A Case Study in Wheat FHB RNA-Seq Data Analysis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- RNA-Seq Data Processing in Plant-Pathogen Interaction System: A Case Study.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Transcriptomic analysis of bakanae disease resistant and susceptible rice genotypes in response to infection by Fusarium fujikuroi.Molecular biology reports · 2022Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundFusarium head blight (FHB) of wheat in North America is caused mostly by the fungal pathogen Fusarium graminearum (Fg). Upon exposure to Fg, wheat initiates a series of cellular responses involving massive transcriptional reprogramming. In this study, we analyzed transcriptomics data of four wheat genotypes (Nyubai, Wuhan 1, HC374, and Shaw), at 2 and 4 days post inoculation (dpi) with Fg, using RNA-seq technology.
resultsA total of 37,772 differentially expressed genes (DEGs) were identified, 28,961 from wheat and 8811 from the pathogen. The susceptible genotype Shaw exhibited the highest number of host and pathogen DEGs, including 2270 DEGs associating with FHB susceptibility. Protein serine/threonine kinases and LRR-RK were associated with susceptibility at 2 dpi, while several ethylene-responsive, WRKY, Myb, bZIP and NAC-domain containing transcription factors were associated with susceptibility at 4 dpi. In the three resistant genotypes, 220 DEGs were associated with resistance. Glutathione S-transferase (GST), membrane proteins and distinct LRR-RKs were associated with FHB resistance across the three genotypes. Genes with unique, high up-regulation by Fg in Wuhan 1 were mostly transiently expressed at 2 dpi, while many defense-associated genes were up-regulated at both 2 and 4 dpi in Nyubai; the majority of unique genes up-regulated in HC374 were detected at 4 dpi only. In the pathogen, most genes showed increased expression between 2 and 4 dpi in all genotypes, with stronger levels in the susceptible host; however two pectate lyases and a hydrolase were expressed higher at 2 dpi, and acetyltransferase activity was highly enriched at 4 dpi.
conclusionsThere was an early up-regulation of LRR-RKs, different between susceptible and resistant genotypes; subsequently, distinct sets of genes associated with defense response were up-regulated. Differences in expression profiles among the resistant genotypes indicate genotype-specific defense mechanisms. This study also shows a greater resemblance in transcriptomics of HC374 to Nyubai, consistent with their sharing of two FHB resistance QTLs on 3BS and 5AS, compared to Wuhan 1 which carries one QTL on 2DL in common with HC374.
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