ArticleBMC geriatrics2018
The prevalence of depressive symptoms in Chinese longevous persons and its correlation with vitamin D status.
Article in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Vitamin D and depression in adults: A systematic review.Biomolecules & biomedicine · 2025Pooled it
- Depressive symptoms and functional dependence in near-centenarians and centenarians: a scoping review.BMC geriatrics · 2026Article
- Towards Objective Major Depressive Disorder Detection: a Systematic Review and Meta-Analysis of Diagnostic Biomarkers.The Psychiatric quarterly · 2025Review
- Relationship between leisure activity and depression in Chinese older adults: chain mediating effect of diet and cognition.BMC geriatrics · 2025Article
- Associations between cardiac structure and function and depressive disorder: A centenarian study in China.Heliyon · 2023Article
- Associations of Serum 25(OH)D, PTH, and β-CTX Levels with All-Cause Mortality in Chinese Community-Dwelling Centenarians.Nutrients · 2022Article
- Anti-Inflammatory Dietary Diversity and Depressive Symptoms among Older Adults: A Nationwide Cross-Sectional Analysis.Nutrients · 2022Article
- Association between immunoglobulin A and depression in Chinese older adults: findings from a cross-sectional study.Immunity & ageing : I & A · 2022Article
- Lower Blood Vitamin D Levels Are Associated with Depressive Symptoms in a Population of Older Adults in Kuwait: A Cross-Sectional Study.Nutrients · 2022Article
- Type of tea consumption and depressive symptoms in Chinese older adults.BMC geriatrics · 2021Article
- Article
- Treatment-Resistant Depression Revisited: A Glimmer of Hope.Journal of personalized medicine · 2021Review
- Vitamin D, Depressive Symptoms, and Covid-19 Pandemic.Frontiers in neuroscience · 2021Article
- Lower serum 25-hydroxycholecalciferol is associated with depressive symptoms in older adults in Southern Brazil.Nutrition journal · 2020Article
- Prevalence of and Risk Factors for Depression Among Older Persons 6 Months After the Lushan Earthquake in China: A Cross-Sectional Survey.Frontiers in psychiatry · 2020Article
- Reliability, Validity, and Factor Structure of Pittsburgh Sleep Quality Index in Community-Based Centenarians.Frontiers in psychiatry · 2020Article
- Associations Between Complement Components and Vitamin D and the Physical Activities of Daily Living Among a Longevous Population in Hainan, China.Frontiers in immunology · 2020Article
- Sex, Residence and Fish Intake Predict Vitamin D Status in Chinese Centenarians.The journal of nutrition, health & aging · 2019Article
- Prevalence of functional dependence in Chinese centenarians and its relationship with serum vitamin D status.Clinical interventions in aging · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypovitaminosis D and depressive syndromes are common conditions in old adults. However, little is known about the relationship between vitamin D and depression in exceptional aged people. The objective of this study is to evaluate the relationship between vitamin D levels and depressive symptoms in Chinese longevous persons.
methodsWe used a dataset from a cross-sectional survey of a sample of Chinese longevous people with self-reported age 100 or older, including 175 men and 765 women, was conducted from June 2014 to December 2016 in Hainan Province, China. Data on demographics, lifestyle characteristics and health conditions were collected using a structured questionnaire. Anthropometrics and blood samples were obtained following the standard procedure. Depressive symptoms of the participants were assessed using a shortened version of the Geriatric Depression Scale (GDS-15). Serum vitamin D levels were measured using an automated radioimmunoassay.
resultsThe prevalence of longevous persons with depressive symptoms among the sample was 32.2% (95% confidence interval: 29.7-34.7%). Serum vitamin D levels were lower in participants with depressive symptoms than in those without (20.8 ± 8.7 vs. 23.7 ± 9.7, ng/mL). Vitamin D deficiency was an independent risk factor for depression after controlling for the potential covariates (Odds ratio = 1.47, 95% Confidence interval = 1.08-2.00; p = 0.014). A negative relationship between serum vitamin D levels and depressive symptoms was also detected, and the relationship remained significant after adjusting for a wide range of other covariates. The multivariate adjusted odds ratio of depressive symptoms for the lowest versus highest quartiles of vitamin D levels was 1.73 (95% confidence interval: 1.10-2.72), and the adjusted odds ratio with a 5 ng/mL decrement of serum 25OHD levels was 1.10 (95% confidence interval: 1.01-1.19).
conclusionsThis study showed an inverse association between vitamin D levels and depressive symptoms among Chinese longevous persons. Depressive symptoms should be screened in longevous persons who had vitamin D deficiency. Further studies on vitamin D supplement and prevention along with treatment of depression are needed among very old population.
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