Evidence map›Paper›PMID 30157111›Full record

ArticleMedicine and science in sports and exercise2019

Walking Ground Reaction Force Post-ACL Reconstruction: Analysis of Time and Symptoms.

Brian Pietrosimone, Matthew K Seeley, Christopher Johnston, Steven J Pfeiffer, Jeffery T Spang, J Troy Blackburn

Open access · greenAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Peak Vertical Ground Reaction Force Modifies Gait Biomechanics Bilaterally Following ACL Reconstruction: A Randomized Experiment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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  12. Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually-Immature Pediatrics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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  16. Aberrant Gait Biomechanics Linked to Cartilage Changes After ACL Reconstruction in Those With High Body Mass Index.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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  20. Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brian PietrosimoneDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Matthew K SeeleyDepartment of Exercise Sciences, Brigham Young University, Provo, UT.
Christopher JohnstonHuman Movement Science Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Steven J PfeifferHuman Movement Science Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Jeffery T SpangDepartment of Orthopaedics, School of Medicine, University of North Carolina at Chapel Hill, NC.
J Troy BlackburnDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC.
University of North Carolina at Chapel Hill · USBrigham Young University · US

Funding

In vivo Manipulation of Mechanical Loading: Using Real-time Biofeedback to Strategically Understand the Acute Biomechanical, Biochemical and Structural Changes Induced by Lower Extremity LoadingR21AR074094 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRANZ, JASON R, PIETROSIMONE, BRIAN · 2018 to 2019
$357k
Posttraumatic Osteoarthritis: Establishing a Comprehensive Evaluation StrategyR03AR066840 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIETROSIMONE, BRIAN · 2015 to 2016
$152k
NIAMS NIH HHS R03 AR066840NIAMS NIH HHS R21 AR074094
6 · The paper itself

Abstract

purposeThe association between lower-extremity loading and clinically relevant knee symptoms at different time points after anterior cruciate ligament reconstruction (ACLR) is unclear. Vertical ground reaction force (vGRF) from walking was compared between individuals with and without clinically relevant knee symptoms in three cohorts: <12 months post-ACLR, 12-24 months post-ACLR, and >24 months post-ACLR.

methodsOne hundred twenty-eight individuals with unilateral ACLR were classified as symptomatic or asymptomatic, based on previously defined cutoff values for the Knee Osteoarthritis and Injury Outcome Score (<12 months post-ACLR [symptomatic n = 28, asymptomatic n = 24]; 12-24 months post-ACLR [symptomatic n = 15, asymptomatic n = 15], and >24 months post-ACLR [symptomatic, n = 13; asymptomatic, n = 33]). Vertical ground reaction force exerted on the ACLR limb was collected during walking gait, and functional analyses of variance were used to evaluate the effects of symptoms and time post-ACLR on vGRF throughout stance phase (α = 0.05).

resultsSymptomatic individuals, <12 months post-ACLR, demonstrated less vGRF during both vGRF peaks (i.e., weight acceptance and propulsion) and greater vGRF during midstance, compared to asymptomatic individuals. Vertical ground reaction force characteristics were not different between symptomatic and asymptomatic individuals for most of stance in individuals between 12 and 24 months post-ACLR. Symptomatic individuals who were >24 months post-ACLR, exhibited greater vGRF during both peaks, but lesser vGRF during midstance, compared to asymptomatic individuals.

conclusionRelative to asymptomatic individuals, symptomatic individuals are more likely to underload the ACLR limb early after ACLR (i.e., <12 months) during both vGRF peaks, but overload the ACLR limb, during both vGRF peaks, at later time points (i.e., >24 months). We propose these differences in lower-extremity loading during walking might have implications for long-term knee health, and should be considered when designing therapeutic interventions for individuals with an ACLR.

Indexed as

Anterior Cruciate Ligament ReconstructionAdolescentAdultAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaCartilage, ArticularCross-Sectional StudiesFemaleHumansLower ExtremityMaleOsteoarthritis, KneePatient Reported Outcome MeasuresRisk FactorsTime FactorsWalking

Identifiers

PMID30157111
PMCPMC6335151
OpenAlexW2889260862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.