Evidence map›Paper›PMID 30157083›Full record

ArticleAIDS (London, England)2018

Impact of bariatric surgery in patients with HIV infection: a nationwide inpatient sample analysis, 2004-2014.

Prabin Sharma, Thomas R McCarty, Julius N Ngu, Michael O'Donnell, Basile Njei

Registry-linked trialAbstract read
In one paragraph

Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04480034 (Laparoscopic Bariatric Surgery During Phase 2-3 Covid-19 Pandemic in Italy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04480034 unknown statusnot on this mapstarted 2020, after this paper: background citation

Laparoscopic Bariatric Surgery During Phase 2-3 Covid-19 Pandemic in Italy: a Multicenter, Prospective, Observational Study.

TypeobservationalSponsorUniversity of Roma La SapienzaRan2020 to 2021Enrolled1,600ConditionsBariatric Surgery Candidate, Covid19, Complication of Surgical Procedure, Pneumonia, ViralArmsBariatric procedures
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. NASH in HIV.Current HIV/AIDS reports · 2020
    Review
  6. Obesity and Weight Gain in Persons with HIV.Current HIV/AIDS reports · 2020 · on this map
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Prabin SharmaDepartment of Internal Medicine, Yale University School of Medicine, New Haven.
Thomas R McCartyDepartment of Internal Medicine, Yale University School of Medicine, New Haven.
Julius N NguDepartment of Surgery, University of Texas Medical Branch, Galveston, Texas.
Michael O'DonnellDepartment of Internal Medicine, Yale University School of Medicine, New Haven.
Basile NjeiSection of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Yale University · USBridgeport Hospital · USThe University of Texas Medical Branch at Galveston · US

Funding

Training Program in Investigative HepatologyT32DK007356 · NIDDK · YALE UNIVERSITY · PI MICHAEL H NATHANSON · 1986 to 2026
$7.4M
NIDDK NIH HHS T32 DK007356
6 · The paper itself

Abstract

objectiveDespite rising rates of obesity among patients with HIV, the potential role for weight loss surgery in this population remains less clear. The primary aim of this study was to evaluate the role of bariatric surgery on relevant clinical outcomes among hospitalized obese patients with HIV.

designRetrospective analysis using the United States Nationwide Inpatient Sample database from 2004 to 2014. Using Poisson regression, adjusted incidence risk ratios (IRR) were derived for clinical outcomes in patients with prior-bariatric surgery compared with those without bariatric surgery. PATIENTS: Patients with discharge co-diagnoses of morbid obesity and HIV.

interventionBariatric surgery.

main outcome measuresPrimary outcome was in-hospital mortality. Secondary outcomes included renal failure, urinary tract infection, malnutrition, sepsis, pneumonia, respiratory failure, thromboembolic events, gastrointestinal strictures, micronutrient deficiency, length of stay, and hospitalization costs.

resultsAmong 7803 patients with discharge diagnoses of HIV and morbid obesity, 346 patients (4.4%) had bariatric surgery. The proportion of bariatric surgery in obese patients with HIV initially declined by -0.10% per year from 2004 to 2009 (Ptrend < 0.05), then increased at an annual rate of +0.33% from 2012 to 2014 (Ptrend < 0.05). On multivariable analysis, bariatric surgery did not influence mortality (P = 0.98). Bariatric surgery was associated with decreased risk for renal failure, respiratory failure, and sepsis (all P < 0.001). However, bariatric surgery increased the risk for postoperative strictures (IRR 2.5; 95% CI 1.5-4.5; P = 0.001).

conclusionThough initially underutilized, bariatric surgery in morbidly obese HIV patients is increasing and appears to be well tolerated and effective in significantly reducing life-threatening morbidity.

Indexed as

Bariatric SurgeryAdultAgedFemaleHIV InfectionsHumansMaleMiddle AgedObesityRetrospective StudiesSurvival AnalysisTreatment OutcomeUnited States

Identifiers

PMID30157083
PMCPMC6126912
OpenAlexW2889027999

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.