ReviewAnais brasileiros de dermatologia
Fogo selvagem: endemic pemphigus foliaceus.
Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 45 citations in OpenAlex.
- Oral Pemphigus in Children and Adolescents: A Narrative Review of Published Case Reports.Reports (MDPI) · 2026Review
- Could vector-derived cadherin mimicry contribute to pemphigus vulgaris? An immunogenetic andFrontiers in immunology · 2026Article
- A case of superficial pemphigus induced by sodium valproate.Oxford medical case reports · 2025Article
- Article
- Clinical Features, Diagnosis and Treatment of Different Types of Paediatric Pemphigus.Acta dermato-venereologica · 2025Article
- A Global View of Pemphigus: Geographical Variations.Clinical reviews in allergy & immunology · 2024Review
- Ultrastructural skin alterations of healthy subjects withJournal of translational autoimmunity · 2023Article
- Two asymptomatic facial erythematous macules in an adult male.Skin health and disease · 2023Article
- The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review.Nutrients · 2022Review
- An Updated Review of Pemphigus Diseases.Medicina (Kaunas, Lithuania) · 2021Review
- Article
- Autoantibody-Specific Signalling in Pemphigus.Frontiers in medicine · 2021Review
- Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus.Genetics and molecular biology · 2020Article
- Pemphigus foliaceus patients (Fogo Selvagem) treated with kinesiotherapy presented lower levels of proinflammatory cytokines.Journal of exercise rehabilitation · 2019Article
- Consensus on the treatment of autoimmune bullous dermatoses: pemphigus vulgaris and pemphigus foliaceus - Brazilian Society of Dermatology.Anais brasileiros de dermatologia · 2019Article
- Epidemiological and clinical study of cases of endemic pemphigus foliaceus and pemphigus vulgaris in a reference center in the state of Minas Gerais, Brazil.Anais brasileiros de dermatologiaObservational
- Successful treatment of erythrodermic pemphigus foliaceus with intravenous immunoglobulin.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fogo selvagem or endemic pemphigus foliaceus is an autoimmune acantholytic anti-cadherin bullous disease that primarily affects seborrheic areas, which might disseminate. Brazil has the world's largest number of patients, mainly in the Central-West region, but the disease has also been reported in other South American countries. It affects young people and adults who have been exposed to rural areas, with occurrence of familial cases. Anti-desmoglein-1 autoantibodies are directed against desmosomal structures, with loss of adhesion of the upper layers of the epidermis, causing superficial blisters. The etiology is multifactorial and includes genetic, immune, and environmental factors, highlighting hematophagous insect bites; drug-related factors are occasionally involved. Flaccid blisters readily rupture to yield erosive-crusty lesions that sometimes resemble seborrheic dermatitis, actinic keratosis, and chronic cutaneous lupus erythematosus. The clinical presentation varies from localized to disseminated lesions. Clinical suspicion should be confirmed with histopathological and immunofluorescence tests, among others. The progression is usually chronic, and therapy varies according to clinical presentation, but generally requires systemic corticosteroid therapy associated with adjuvant immunosuppressive treatment to decrease the adverse effects of corticosteroids. Once the disease is under control, many patients remain stable on low-dose medication, and a significant proportion achieve remission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.