Evidence map›Paper›PMID 30156436›Full record

Trial reportJournal of medicinal food2018

Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study.

Muhammed Majeed, Shaheen Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Anurag Pande, Mahesh Paschapur, Furqan Ali

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medicinal food, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. The Role of Pancreatic Enzyme Insufficiency in the Etiology of Functional Dyspepsia Resistant to Standard Treatment.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  3. Journal of microbiology and biotechnology · 2025
    Article
  4. Article
  5. Heliyon · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Muhammed Majeed1 Sami Labs Limited , Bangalore, Karnataka, India .
Shaheen Majeed1 Sami Labs Limited , Bangalore, Karnataka, India .
Kalyanam Nagabhushanam2 Sabinsa Corporation , East Windsor, New Jersey, USA.
Sivakumar Arumugam1 Sami Labs Limited , Bangalore, Karnataka, India .
Anurag Pande2 Sabinsa Corporation , East Windsor, New Jersey, USA.
Mahesh Paschapur1 Sami Labs Limited , Bangalore, Karnataka, India .
Furqan Ali1 Sami Labs Limited , Bangalore, Karnataka, India .
Sami Labs (India) · INSabin Vaccine Institute · USSeaWorld Entertainment · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional dyspepsia (FD) is a highly prevalent disorder having nonspecific symptoms and varied pathophysiology. Its treatment remains a challenge as therapeutic options are limited, unsatisfactory, and elusive. Thus, safety and efficacy of DigeZyme

Indexed as

Enzyme TherapyAdolescentAdultAgedDouble-Blind MethodDyspepsiaEnzymesFemaleHumansIndiaMaleMiddle AgedSurveys and QuestionnairesYoung AdultEnzymesdigestive enzymesdyspeptic symptomsfunctional dyspepsiamultienzyme complexnonulcer dyspepsiasafety and efficacy

Identifiers

PMID30156436
PMCPMC6249666
OpenAlexW2889241372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.