ArticleJournal of neural engineering2018
A head mounted device stimulator for optogenetic retinal prosthesis.
Article in Journal of neural engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Evaluating the Efficacy of Smart Saliency Detection System for Visual Prosthesis Users: An Experimental Comparison Across Various Visual Prosthesis Implants.Artificial organs · 2026Article
- Bionic vision technologies: progress and perspectives on retinal prostheses and optogenetics for the treatment of advanced retinal degeneration.Frontiers in medical technology · 2026Review
- Regulatory aspects of optogenetic research and therapy for retinitis pigmentosa under EU law.Frontiers in medical technology · 2025Review
- Theoretical prediction of broadband ambient light optogenetic vision restoration with ChRmine and its mutants.Scientific reports · 2024Article
- Ethics and regulation of neuronal optogenetics in the European Union.Pflugers Archiv : European journal of physiology · 2023Review
- REDOX Balance in Oligodendrocytes Is Important for Zebrafish Visual System Regeneration.Antioxidants (Basel, Switzerland) · 2023Article
- A clinically viable approach to restoring visual function using optogenetic gene therapy.Molecular therapy. Methods & clinical development · 2023Article
- Human cornea thermo-viscoelastic behavior modelling using standard linear solid model.BMC ophthalmology · 2023Article
- Activation of retinal ganglion cells using a biomimetic artificial retina.Journal of neural engineering · 2021Article
- Restoring vision at the fovea.Current opinion in behavioral sciences · 2019Article
- High Density, Double-Sided, Flexible Optoelectronic Neural Probes With Embedded μLEDs.Frontiers in neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveOur main objective is to demonstrate that compact high radiance gallium nitride displays can be used with conventional virtual reality optics to stimulate an optogenetic retina. Hence, we aim to introduce a non-invasive approach to restore vision for people with conditions such as retinitis pigmentosa where there is a remaining viable communication link between the retina and the visual cortex. APPROACH: We design and implement the headset using a high-density µLED matrix, Raspberry Pi, microcontroller from NXP and virtual reality lens. Then, a test platform is developed to evaluate the performance of the headset and the optical system. Furthermore, image simplification algorithms are used to simplify the scene to be sent to the retina. Moreover, in vivo evaluation of the genetically modified retina response at different light intensity is discussed to prove the reliability of the proposed system. MAIN
resultsWe demonstrate that in keeping with regulatory guidance, the headset displays need to limit their luminance to 90 kcd m SIGNIFICANCE: We demonstrate a fully functional 8100-pixel headset system including software/hardware which can operate on a standard consumer battery for periods exceeding a 24 h recharge cycle. The headset is capable of delivering enough light to stimulate the genetically modified retina cells and also keeping the amount of light below the regulation threshold for safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.