ArticleHippocampus2018
Remembering rewarding futures: A simulation-selection model of the hippocampus.
Article in Hippocampus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- A likelihood-based method for identifying replay from spike sequences.Nature communications · 2026Article
- Selective reactivation of value- and place-dependent information during sharp-wave ripples in the intermediate and dorsal hippocampus.Science advances · 2024Article
- Memory consolidation from a reinforcement learning perspective.Frontiers in computational neuroscience · 2024Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.Current biology : CB · 2023Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.bioRxiv : the preprint server for biology · 2023Article
- Blue-Light-Blocking Lenses Ameliorate Structural Alterations in the Rodent Hippocampus.International journal of environmental research and public health · 2022Article
- Correcting the hebbian mistake: Toward a fully error-driven hippocampus.PLoS computational biology · 2022Article
- Space, feature, and risk sensitivity in homing pigeons (Columba livia): Broadening the conversation on the role of the avian hippocampus in memory.Learning & behavior · 2022Article
- Navigating for reward.Nature reviews. Neuroscience · 2021Review
- Cortical reactivations of recent sensory experiences predict bidirectional network changes during learning.Nature neuroscience · 2020Article
- Flexible use of allocentric and egocentric spatial memories activates differential neural networks in mice.Scientific reports · 2020Article
- Distinct effects of reward and navigation history on hippocampal forward and reverse replays.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite tremendous progress, the neural circuit dynamics underlying hippocampal mnemonic processing remain poorly understood. We propose a new model for hippocampal function-the simulation-selection model-based on recent experimental findings and neuroecological considerations. Under this model, the mammalian hippocampus evolved to simulate and evaluate arbitrary navigation sequences. Specifically, we suggest that CA3 simulates unexperienced navigation sequences in addition to remembering experienced ones, and CA1 selects from among these CA3-generated sequences, reinforcing those that are likely to maximize reward during offline idling states. High-value sequences reinforced in CA1 may allow flexible navigation toward a potential rewarding location during subsequent navigation. We argue that the simulation-selection functions of the hippocampus have evolved in mammals mostly because of the unique navigational needs of land mammals. Our model may account for why the mammalian hippocampus has evolved not only to remember, but also to imagine episodes, and how this might be implemented in its neural circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.