Evidence map›Paper›PMID 30155768›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2018

Stimulation of angiogenesis using single-pulse low-pressure shock wave treatment.

Susinder Sundaram, Karthi Sellamuthu, Krishnaveni Nagavelu, Harikumar R Suma, Arpan Das, Raghu Narayan, Dipshikha Chakravortty, Jagadeesh Gopalan, Sandeep M Eswarappa

Abstract read
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In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Susinder SundaramDepartment of Biochemistry, Indian Institute of Science, Bengaluru, India.
Karthi SellamuthuDepartment of Biochemistry, Indian Institute of Science, Bengaluru, India.
Krishnaveni NagaveluCentral Animal Facility, Indian Institute of Science, Bengaluru, India.
Harikumar R SumaDepartment of Biochemistry, Indian Institute of Science, Bengaluru, India.
Arpan DasDepartment of Biochemistry, Indian Institute of Science, Bengaluru, India.
Raghu NarayanDepartment of Aerospace Engineering, Indian Institute of Science, Bengaluru, India.
Dipshikha ChakravorttyDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru, India.
Jagadeesh GopalanDepartment of Aerospace Engineering, Indian Institute of Science, Bengaluru, India. jaggie@iisc.ac.in.
Sandeep M EswarappaDepartment of Biochemistry, Indian Institute of Science, Bengaluru, India. sandeep@iisc.ac.in.ORCID 0000-0002-7903-5198
Indian Institute of Science Bangalore · IN

Funding

DBT India Alliance IA/I/15/1/501833Science and Engineering Research Board YSS/2015/000989
6 · The paper itself

Abstract

Endothelial cells respond to mechanical stimuli such as stretch. This property can be exploited with caution to induce angiogenesis which will have immense potential to treat pathological conditions associated with insufficient angiogenesis. The primary aim of this study is to test if low-pressure shock waves can be used to induce angiogenesis. Using a simple diaphragm-based shock tube, we demonstrate that a single pulse of low pressure (0.4 bar) shock wave is enough to induce proliferation in bovine aortic endothelial cells and human pulmonary microvascular endothelial cells. We show that this is associated with enhanced Ca

Indexed as

Extracorporeal Shockwave TherapyNeovascularization, PhysiologicAnimalsCattleCell MovementCell ProliferationEndothelial CellsFemaleHumansMice, Inbred BALB CAngiogenesisEndothelial cellsShock wavesWound healing

Identifiers

PMID30155768
OpenAlexW2888887998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.