Evidence map›Paper›PMID 30155679›Full record

ReviewChinese journal of integrative medicine2019

Effects of Acupuncture on Alzheimer's Disease: Evidence from Neuroimaging Studies.

Chao-Chao Yu, Chao-Yang Ma, Hua Wang, Li-Hong Kong, Yan Zhao, Feng Shen, Miao Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chinese journal of integrative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chao-Chao YuCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, 430061, China.
Chao-Yang MaDepartment of Rehabilitation, Wuhan Central Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China.
Hua WangCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, 430061, China.
Li-Hong KongCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, 430061, China. xiyu1618@sina.com.
Yan ZhaoHubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.
Feng ShenCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, 430061, China.
Miao WuHubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.
Hubei University of Chinese Medicine · CNHubei Provincial Hospital of Traditional Chinese Medicine · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the worldwide population ages, the prevalence of Alzheimer's disease (AD) increases. However, the results of promising medications have been unsatisfactory. Chinese acupuncture has a long history of treating dementia, but lack of evidence from well-designed randomized controlled trials that validate its efficacy and safety, as well as its lack of clear underlying mechanisms, contribute to its limited application in clinical practice. In recent years, brain imaging technologies, such as functional magnetic resonance imaging and positron emission tomography, have been used to assess brain responses to acupuncture in a dynamic, visual, and objective way. These techniques are frequently used to explore neurological mechanisms of responses to acupuncture in AD and provide neuroimaging evidence as well as starting points to elucidate the possible mechanisms. This review summarizes the existing brain imaging evidence that explains the effects of acupuncture for AD and analyzes brain responses to acupuncture at cognitive-related acupoints [Baihui (GV 20), Shenmen (HT 7), Zusanli (ST 36), Neiguan (PC 6), and Taixi (KI 3)] from perspectives of acupoint specificity and acupoint combinations. Key issues and directions to consider in future studies are also put forward. This review should deepen our understanding of how brain imaging studies can be used to explore the underlying mechanisms of acupuncture in AD.

Indexed as

Acupuncture TherapyNeuroimagingAcupuncture PointsAlzheimer DiseaseBrainHumansacupoint specificityacupunctureAlzheimer's diseasebrain responseneuroimaging

Identifiers

PMID30155679
OpenAlexW2889356640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.