Evidence map›Paper›PMID 30155669›Full record

ArticleJournal of materials science. Materials in medicine2018

Enhanced corrosion resistance and cytocompatibility of biomimetic hyaluronic acid functionalised silane coating on AZ31 Mg alloy for orthopaedic applications.

Sankalp Agarwal, Marie-Noelle Labour, David Hoey, Brendan Duffy, James Curtin, Swarna Jaiswal

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Surface Coatings on Biomedical Magnesium Alloys.Materials (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sankalp AgarwalCentre for Research in Engineering and Surface Technology, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland.
Marie-Noelle LabourTrinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
David HoeyTrinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
Brendan DuffyCentre for Research in Engineering and Surface Technology, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland.
James CurtinSchool of Food Science and Environmental Health, Cathal Brugha Street, Dublin Institute of Technology, Dublin 1, Ireland.
Swarna JaiswalCentre for Research in Engineering and Surface Technology, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland. swarna.jaiswal@dit.ie.
Centre for Research in Engineering Surface Technology · IERoyal College of Surgeons in Ireland · IETrinity College Dublin · IE

Funding

Dublin Institute of Technology Fiosraigh Scholarship Programme 2014
6 · The paper itself

Abstract

This paper reports the corrosion resistant and cytocompatible properties of the hyaluronic acid-silane coating on AZ31 Mg alloy. In this study, the osteoinductive properties of high molecular weight hyaluronic acid (HA, 1-4 MDa) and the corrosion protection of silane coatings were incorporated as a composite coating on biodegradable AZ31 Mg alloy for orthopaedic applications. The multi-step fabrication of coatings first involved dip coating of a passivated AZ31 Mg alloy with a methyltriethoxysilane-tetraethoxysilane sol-gel to deposit a dense, cross-linked and corrosion resistant silane coating (AZ31-MT). The second step was to create an amine-functionalised surface by treating coated alloy with 3-aminopropyl-triethoxy silane (AZ31-MT-A) which facilitated the immobilisation of HA via EDC-NHS coupling reactions at two different concentrations i.e 1 mg.ml

Indexed as

Biocompatible Materials3T3 CellsAlloysAnimalsCell SurvivalElectrochemistryHyaluronic AcidHydrogenHydrogen-Ion ConcentrationMagnesium CompoundsMaterials TestingMiceOsteoblastsProstheses and ImplantsSilanesSurface PropertiesAlloysBiocompatible MaterialsHyaluronic AcidHydrogenMagnesium CompoundsSilanes

Identifiers

PMID30155669
OpenAlexW2888846434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.