Evidence map›Paper›PMID 30155618›Full record

SynthesisWorld journal of pediatrics : WJP2018

Chinese guidelines for the assessment and provision of nutrition support therapy in critically ill children.

Xue-Mei Zhu, Su-Yun Qian, Guo-Ping Lu, Feng Xu, Ying Wang, Chun-Feng Liu, Xiao-Xu Ren, Yu-Cai Zhang, Heng-Miao Gao, Tao Zhou and 3 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
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In one paragraph

Synthesis in World journal of pediatrics : WJP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Xue-Mei ZhuChildren's Hospital, Fudan University, No. 399 Wanyuan Road, Minhang District, 201100, Shanghai, China.ORCID http://orcid.org/0000-0002-8297-3206
Su-Yun QianBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nan-li-shi Road, Xicheng District, 100045, Beijing, China. syqian1211@163.com.
Guo-Ping LuChildren's Hospital, Fudan University, No. 399 Wanyuan Road, Minhang District, 201100, Shanghai, China.
Feng XuChildren's Hospital of Chongqing Medical University, 136 Zhongshan No. 2 Road, Yu Zhong District, 400010, Chongqing, China.
Ying WangShanghai Children's Medical Center, No. 1678, DongFang Road, 200127, Shanghai, China.
Chun-Feng LiuShengjing Hospital of China Medical University, No.36 Sanhao Road, 110004, Shenyang, China.
Xiao-Xu RenThe Capital Institute of Pediatrics, No. 2 Yabao Road, 100020, Beijing, China.
Yu-Cai ZhangShanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, 200062, Shanghai, China.
Heng-Miao GaoBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nan-li-shi Road, Xicheng District, 100045, Beijing, China.
Tao ZhouBoai Hospital of Zhongshan Affiliated to Southern Medical University, 6 Chenggui Road, East District, 528400, Zhongshan, China.
Hong-Xing DangChildren's Hospital of Chongqing Medical University, 136 Zhongshan No. 2 Road, Yu Zhong District, 400010, Chongqing, China.
Chong-Fan ZhangChildren's Hospital, Fudan University, No. 399 Wanyuan Road, Minhang District, 201100, Shanghai, China.
Yi-Min ZhuHunan Provincial People's Hospital, No. 60 Jiefang West Road, 410005, Changsha, China.
Boai Hospital of Zhongshan · CNCapital Medical University · CNChildren's Hospital of Chongqing Medical University · CNChildren's Hospital of Fudan University · CNCapital Institute of Pediatrics · CNChina Medical University · CNHunan Provincial People's Hospital · CNShanghai Children's Medical Center · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis document represents the first evidence-based guidelines to describe best practices in nutrition therapy in critically ill children (> 1 month and < 18 years), who are expected to require a length of stay more than 2 or 3 days in a Pediatric Intensive Care Unit admitting medical patients domain.

methodsA total of 25,673 articles were scanned for relevance. After careful review, 88 studies appeared to answer the pre-identified questions for the guidelines. We used the grading of recommendations, assessment, development and evaluation criteria to adjust the evidence grade based on the quality of design and execution of each study.

resultsThe guidelines emphasise the importance of nutritional assessment, particularly the detection of malnourished patients. Indirect calorimetry (IC) is recommended to estimate energy expenditure and there is a creative value in energy expenditure, 50 kcal/kg/day for children aged 1-8 years during acute phase if IC is unfeasible. Enteral nutrition (EN) and early enteral nutrition remain the preferred routes for nutrient delivery. A minimum protein intake of 1.5 g/kg/day is suggested for this patient population. The role of supplemental parenteral nutrition (PN) has been highlighted in patients with low nutritional risk, and a delayed approach appears to be beneficial in this group of patients. Immune-enhancing cannot be currently recommended neither in EN nor PN.

conclusionOverall, the pediatric critically ill population is heterogeneous, and an individualized nutrition support with the aim of improving clinical outcomes is necessary and important.

Indexed as

Nutritional RequirementsPractice Guidelines as TopicAdolescentChildChild, PreschoolChinaCritical CareCritical IllnessEnergy MetabolismEnteral NutritionFemaleHumansInfantIntensive Care Units, PediatricMaleNutritional StatusAdolescentsChildrenCritical illnessEnteral nutritionIndirect calorimetryInfantMalnutritionNutrition assessmentParenteral nutritionPediatricResting energy expenditure

Identifiers

PMID30155618
OpenAlexW2889156790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.