Evidence map›Paper›PMID 30155616›Full record

ArticleWorld journal of pediatrics : WJP2018

Calcium-handling abnormalities underlying atrial arrhythmogenesis in a Fontan operation canine model.

Wan-Ping Zhou, Fen Li, Jin-Jin Wu, Ya-Nan Lu, Yi-Jiao Qian

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of pediatrics : WJP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wan-Ping ZhouCardiology Department, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Pudong New Area, 200127, Shanghai, China.ORCID http://orcid.org/0000-0002-4124-8665
Fen LiCardiology Department, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Pudong New Area, 200127, Shanghai, China. lifen@scmc.com.cn.
Jin-Jin WuCardiology Department, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Pudong New Area, 200127, Shanghai, China.
Ya-Nan LuCardiology Department, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Pudong New Area, 200127, Shanghai, China.
Yi-Jiao QianCardiology Department, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, 1678 Dongfang Road, Pudong New Area, 200127, Shanghai, China.
Shanghai Children's Medical Center · CNSoochow University · CN

Funding

Scientific Research Program of Shanghai Science and Technology Commission 13430721700The Jiangsu Provincial Medical Youth Talent QNRC2016761The National Natural Science Foundation of China 81300138The National Natural Science Foundation of China 81870248
6 · The paper itself

Abstract

backgroundAtrial tachyarrhythmia (AT) is a common complication in patients who have undergone a Fontan operation. In this study, we investigated whether abnormal Ca

methodsMongrel dogs were randomly assigned to sham and Fontan groups. The Fontan operation model was developed by performing an atriopulmonary anastomosis. After 14 days, an electrophysiological study was performed to evaluate the AT vulnerability. Ca

resultsThe AT inducibility was higher in the Fontan group than in the sham group (85.71 vs. 14.29%, P < 0.05). The Fontan operation resulted in decreased Ca

conclusionThe Fontan operation caused atrial CM Ca

Indexed as

AnimalsAtrial FibrillationCalciumDogsFontan ProcedureFura-2Heart AtriaModels, AnimalMyocardiumMyocytes, CardiacPatch-Clamp TechniquesSarcoplasmic ReticulumSodium-Calcium ExchangerCalciumFura-2fura-2-amSodium-Calcium Exchangersodium-calcium exchanger 1Atrial tachyarrhythmiaCalcium handlingFontan operationTriggered activity

Identifiers

PMID30155616
OpenAlexW2889328300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.