Evidence map›Paper›PMID 30155584›Full record

ReviewCurrent psychiatry reports2018

Psychosocial Treatments Targeting Anxiety and Depression in Adolescents and Adults on the Autism Spectrum: Review of the Latest Research and Recommended Future Directions.

Susan W White, Grace Lee Simmons, Katherine O Gotham, Caitlin M Conner, Isaac C Smith, Kelly B Beck, Carla A Mazefsky

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current psychiatry reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Improving Transition to Adulthood for Students with Autism: A Randomized Controlled Trial of STEPS.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Trial
  11. Article
  12. Exploring Patterns of Self-Harm in Autistic Adults Using the Card Sort Task for Self-Harm.Autism : the international journal of research and practice · 2026
    Article
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  19. Article
  20. Review

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susan W WhiteDepartment of Psychology, University of Alabama, Box 870348, Tuscaloosa, AL, 35487-0348, USA. swwhite1@ua.edu.
Grace Lee SimmonsDepartment of Psychology, University of Alabama, Box 870348, Tuscaloosa, AL, 35487-0348, USA.
Katherine O GothamDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Caitlin M ConnerDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Isaac C SmithDepartment of Psychology, University of Alabama, Box 870348, Tuscaloosa, AL, 35487-0348, USA.
Kelly B BeckClinical Rehabilitation and Mental Health Counseling, School of Health and Rehabilitation Sciences, Pittsburgh, PA, USA.
Carla A MazefskyDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

Change-sensitive Measurement of Emotion Dysregulation in ASDR01HD079512 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carla A Mazefsky · 2014 to 2026
$6.3M
Repetitive Thinking and Emotional Health in Adults with ASDR01MH113576 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOTHAM, KATHERINE O · 2018 to 2022
$2.0M
Autism Spectrum Disorders and Depression: Shared Mechanisms in Brain and BehaviorK01MH103500 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOTHAM, KATHERINE O · 2014 to 2017
$640k
NICHD NIH HHS R01 HD079512NIMH NIH HHS K01 MH103500NIMH NIH HHS R01 MH113576
6 · The paper itself

Abstract

purpose of reviewThis synthesis of treatment research related to anxiety and depression in adolescents and adults with autism spectrum disorder (ASD) focuses on the scientific support for various forms of psychosocial interventions, useful adaptations to standard interventions, and engagement of candidate therapeutic mechanisms. RECENT

findingsThere is considerable evidence for the efficacy of cognitive-behavioral therapy (CBT) to treat co-occurring problems with anxiety, but there has been relatively little research on treatment of co-occurring depression. Multiple mechanisms of treatment effect have been proposed, but there has been little demonstration of target engagement via experimental therapeutics. Comorbidity between ASD and anxiety and/or mood problems is common. Although there is evidence for the use of CBT for anxiety, little work has addressed how to effectively treat depression. There is emerging support for alternative treatment approaches, such as mindfulness-based interventions. We encourage rigorous, collaborative approaches to identify and manipulate putative mechanisms of change.

Indexed as

AdolescentAdultAnxietyAnxiety DisordersAutism Spectrum DisorderCognitive Behavioral TherapyDepressionDepressive DisorderHumansMindfulnessAnxietyAutismCognitive-behavioral therapy (CBT)DepressionInterventionMindfulness

Identifiers

PMID30155584
PMCPMC6421847

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.