Evidence map›Paper›PMID 30155518›Full record

ArticleNPJ breast cancer2018

Sentinel lymph node B cells can predict disease-free survival in breast cancer patients.

Kim R M Blenman, Ting-Fang He, Paul H Frankel, Nora H Ruel, Erich J Schwartz, David N Krag, Lee K Tan, John H Yim, Joanne E Mortimer, Yuan Yuan and 1 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hub gene of disulfidptosis-related immune checkpoints in breast cancer.Medical oncology (Northwood, London, England) · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. B cell receptor signaling strength modulates cancer immunity.The Journal of clinical investigation · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Kim R M Blenman1Department of Immuno-Oncology, City of Hope and Beckman Research Institute, Duarte, CA USA.
Ting-Fang He1Department of Immuno-Oncology, City of Hope and Beckman Research Institute, Duarte, CA USA.
Paul H Frankel2Department of Biostatistics, City of Hope and Beckman Research Institute, Duarte, CA USA.
Nora H Ruel2Department of Biostatistics, City of Hope and Beckman Research Institute, Duarte, CA USA.
Erich J Schwartz3Department of Pathology, Stanford University, Stanford, CA USA.
David N Krag4Department of Surgery, University of Vermont College of Medicine, Burlington, VT USA.
Lee K Tan5Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY USA.
John H Yim6Department of Surgery, City of Hope and Beckman Research Institute, Duarte, CA USA.
Joanne E Mortimer7Department of Women's Health, City of Hope and Beckman Research Institute, Duarte, CA USA.
Yuan Yuan7Department of Women's Health, City of Hope and Beckman Research Institute, Duarte, CA USA.
Peter P Lee1Department of Immuno-Oncology, City of Hope and Beckman Research Institute, Duarte, CA USA.
Beckman Research InstituteCity of Hope · USMemorial Sloan Kettering Cancer Center · USStanford University · USUniversity of Vermont · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Immune Profile Analysis of Tumor-Draining Lymph Nodes in Breast CancerR01CA127947 · NCI · STANFORD UNIVERSITY · PI LEE, PETER POON-HANG · 2007 to 2011
$1.8M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA127947
6 · The paper itself

Abstract

Tumor invasion into draining lymph nodes, especially sentinel lymph nodes (SLNs), is a key determinant of prognosis and treatment in breast cancer as part of the TNM staging system. Using multicolor histology and quantitative image analysis, we quantified immune cells within SLNs from a discovery cohort of 76 breast cancer patients. We found statistically more in situ CD3

Identifiers

PMID30155518
PMCPMC6107630
OpenAlexW2885161819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.