ArticlePeerJ2018
Eye movement control during visual pursuit in Parkinson's disease.
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Portable eye-tracking in neurology: current uses and future perspectives in cognition.Arquivos de neuro-psiquiatria · 2026Pooled it
- Portable eye-tracking as a reliable assessment of oculomotor, cognitive and reaction time function: Normative data for 18-45 year old.PloS one · 2021Trial
- Residual Foveal Motion Facilitates Processing of Visually Tracked Objects.bioRxiv : the preprint server for biology · 2025Article
- Fixation Stability of the Right and Left Eyes Under Binocular and Monocular Viewing Conditions.Life (Basel, Switzerland) · 2025Article
- Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease.Annals of clinical and translational neurology · 2025Article
- Detecting Abnormal Eye Movements in Patients with Neurodegenerative Diseases - Current Insights.Eye and brain · 2024Review
- Noradrenergic modulation of saccades in Parkinson's disease.Brain communications · 2024Article
- Objective assessment of eye alignment and disparity-driven vergence in Parkinson's disease.Frontiers in aging neuroscience · 2023Article
- Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People.Geriatrics (Basel, Switzerland) · 2021Article
- Abnormalities of smooth pursuit in Parkinson's disease: A systematic review.Clinical parkinsonism & related disorders · 2021Review
- High-resolution, ultrafast, wide-field retinal eye-tracking for enhanced quantification of fixational and saccadic motion.Biomedical optics express · 2020Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrior studies of oculomotor function in Parkinson's disease (PD) have either focused on saccades without considering smooth pursuit, or tested smooth pursuit while excluding saccades. The present study investigated the control of saccadic eye movements during pursuit tasksand assessed the quality of binocular coordinationas potential sensitive markers of PD.
methodsObservers fixated on a central cross while a target moved toward it. Once the target reached the fixation cross, observers began to pursue the moving target. To further investigate binocular coordination, the moving target was presented on both eyes (binocular condition), or on one eye only (dichoptic condition).
resultsThe PD group made more saccades than age-matched normal control adults (NC) both during fixation and pursuit. The difference between left and right gaze positions increased over time during the pursuit period for PD but not for NC. The findings were not related to age, as NC and young-adult control group (YC) performed similarly on most of the eye movement measures, and were not correlated with classical measures of PD severity (e.g., Unified Parkinson's Disease Rating Scale (UPDRS) score). DISCUSSION: Our results suggest that PD may be associated with impairment not only in saccade inhibition, but also in binocular coordination during pursuit, and these aspects of dysfunction may be useful in PD diagnosis or tracking of disease course.
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