Evidence map›Paper›PMID 30155279›Full record

ReviewJournal of transplantation2018

Drug-Induced Hematological Cytopenia in Kidney Transplantation and the Challenges It Poses for Kidney Transplant Physicians.

Muhammad Abdul Mabood Khalil, Muhammad Ashhad Ullah Khalil, Taqi F Taufeeq Khan, Jackson Tan

Abstract readReview
In one paragraph

Review in Journal of transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Living with a transplanted liver is associated with cytopenias: a nationwide cohort study.Frontiers in gastroenterology (Lausanne, Switzerland) · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Adverse Drug Events after Kidney Transplantation.Journal of personalized medicine · 2023
    Review
  11. Article
  12. Article
  13. Anemia after kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Abdul Mabood KhalilRIPAS Hospital, Bandar Seri Begawan BA1710, Brunei Darussalam.ORCID 0000-0003-2378-7339
Muhammad Ashhad Ullah KhalilInstitute of Kidney Diseases, Hayatabad, Peshawar 25000, KPK, Pakistan.
Taqi F Taufeeq KhanKing Salman Armed Forces Hospital, Tabuk King Abdul Aziz Rd., Tabuk 47512, Saudi Arabia.
Jackson TanRIPAS Hospital, Bandar Seri Begawan BA1710, Brunei Darussalam.ORCID 0000-0002-8176-9393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced hematological cytopenia is common in kidney transplantation. Various cytopenia including leucopenia (neutropenia), thrombocytopenia, and anemia can occur in kidney transplant recipients. Persistent severe leucopenia or neutropenia can lead to opportunistic infections of various etiologies. On the contrary, reducing or stopping immunosuppressive medications in these events can provoke a rejection. Transplant clinicians are often faced with the delicate dilemma of balancing cytopenia and rejection from adjustments of immunosuppressive regimen. Differentials of drug-induced cytopenia are wide. Identification of culprit medication and subsequent modification is also challenging. In this review, we will discuss individual drug implicated in causing cytopenia and correlate it with corresponding literature evidence.

Identifiers

PMID30155279
PMCPMC6093016

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.