Evidence map›Paper›PMID 30155209›Full record

ArticleChemical science2017

Structure and conserved function of iso-branched sphingoid bases from the nematode

J Thomas Hannich, Denia Mellal, Suihan Feng, Andreas Zumbuehl, Howard Riezman

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  3. Long Chain Base Profiling with Multiple Reaction Monitoring Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. The lipidomes ofAging · 2023
    Article
  9. Defining the glucosylceramide population ofFrontiers in physiology · 2023
    Review
  10. Article
  11. Article
  12. Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases.Advances in experimental medicine and biology · 2022
    Review
  13. Article
  14. Review
  15. Quo VadisMetabolites · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J Thomas HannichDepartment of Biochemistry , University of Geneva , CH-1205 Geneva , Switzerland . Email: howard.riezman@unige.ch.ORCID 0000-0002-2286-4956
Denia MellalDepartment of Chemistry , University of Fribourg , CH-1700 Fribourg , Switzerland . Email: andreas.zumbuehl@unifr.ch.
Suihan FengDepartment of Biochemistry , University of Geneva , CH-1205 Geneva , Switzerland . Email: howard.riezman@unige.ch.
Andreas ZumbuehlDepartment of Chemistry , University of Fribourg , CH-1700 Fribourg , Switzerland . Email: andreas.zumbuehl@unifr.ch.ORCID 0000-0002-8003-4432
Howard RiezmanDepartment of Biochemistry , University of Geneva , CH-1205 Geneva , Switzerland . Email: howard.riezman@unige.ch.ORCID 0000-0003-4680-9422
University of Geneva · CHUniversity of Fribourg · CH

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Sphingolipids are bio-active metabolites that show structural diversity among eukaryotes. They are essential for growth of all eukaryotic cells but when produced in an uncontrolled manner can lead to cell death and pathologies including auto-immune reactions, cancer, diabetes and neurodegeneration.

Identifiers

PMID30155209
PMCPMC6094178
OpenAlexW2591770202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.