ArticleChemical science2017
AIE-active theranostic system: selective staining and killing of cancer cells.
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 212 citations in OpenAlex.
- Visualized Enzyme-Activated Fluorescence Probe for Accurately Detecting β-Gal in Living Cells and BALB/c Nude Mice.Journal of fluorescence · 2025Article
- Precise visualization and ROS-dependent photodynamic therapy of colorectal cancer with a novel mitochondrial viscosity photosensitive fluorescent probe.Biomaterials research · 2023Article
- Mitochondria Targeted AIE Probes for Cancer Phototherapy.ACS omega · 2023Review
- Visualization of Mitochondria During Embryogenesis in Zebrafish by Aggregation-Induced Emission Molecules.Molecular imaging and biology · 2022Article
- Upconversion Nanostructures Applied in Theranostic Systems.International journal of molecular sciences · 2022Review
- Supramolecular cuboctahedra with aggregation-induced emission enhancement and external binding ability.Chemical science · 2022Article
- Structure and functions of Aggregation-Induced Emission-Photosensitizers in anticancer and antimicrobial theranostics.Frontiers in chemistry · 2022Review
- "Smart" drug delivery: A window to future of translational medicine.Frontiers in chemistry · 2022Review
- A Dual-Labeling Probe for Super-Resolution Imaging to Detect Mitochondrial Reactive Sulfur Species in Live Cells.Frontiers in pharmacology · 2022Article
- Aggregation-induced emission luminogens for image-guided surgery in non-human primates.Nature communications · 2021Article
- Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation.Chemical science · 2021Article
- Recent advances of AIE light-up probes for photodynamic therapy.Chemical science · 2021Review
- Article
- Synthesis, micellar structures and emission mechanisms of an AIE and DDED-featured fluorescent pH- and thermo-meter.RSC advances · 2020Article
- Cancer cell discrimination and dynamic viability monitoring through wash-free bioimaging using AIEgens.Chemical science · 2020Article
- Identification and Single-Cell Analysis of Viable Circulating Tumor Cells by a Mitochondrion-Specific AIE Bioprobe.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens.Chemical science · 2020Article
- Nanoparticle-based Cell Trackers for Biomedical Applications.Theranostics · 2020Review
- Fluorescent probes for organelle-targeted bioactive species imaging.Chemical science · 2019Review
- AIE-based theranostic systems for detection and killing of pathogens.Theranostics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is the leading cause of death worldwide. With the advantages of low cost, high sensitivity and ease of accessibility, fluorescence imaging has been widely used for cancer detection in the scientific field. Aggregation-induced emission luminogens (AIEgens) are a class of synthesized fluorescent probes with high brightness and photostability in the aggregate state. Herein, a new positively-charged AIEgen, abbreviated as TPE-IQ-2O, is designed and characterized. TPE-IQ-2O not only can distinguish cancer cells from normal cells with high contrast with the aid of the difference in mitochondrial membrane potential as well as the quantity of mitochondria, but it also works as a promising photosensitizer to kill cancer cells through generation of reactive oxygen species upon white light irradiation, thus making it a promising AIE theranostic system.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.