ArticleChemical science2016
NIR in, far-red out: developing a two-photon fluorescent probe for tracking nitric oxide in deep tissue.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 135 citations in OpenAlex.
- A Subtle Twist on Sensor Design: NO-Induced Nitration-Triggered C-C Bond Cleavage.Chemical & biomedical imaging · 2026Article
- Recent Advances in the ESIPT-based Responsive Probes for the Detection of Bio-Active Molecules CO, NO and H₂S.Journal of fluorescence · 2026Review
- Organic probes for NO-activatable biomedical imaging: NIR fluorescence, self-luminescence, and photoacoustic imaging.Chemical science · 2025Review
- Nitric Oxide Signaling and Sensing in Age-Related Diseases.Antioxidants (Basel, Switzerland) · 2024Review
- A two-photon ratiometric fluorescent probe for real-time imaging and quantification of NO in neural stem cells during activation regulation.Chemical science · 2022Article
- Small-molecule fluorescent probes based on covalent assembly strategy for chemoselective bioimaging.RSC advances · 2022Review
- Thiophene and diaminobenzo- (1,2,5-thiadiazol)- based DAD-type near-infrared fluorescent probe for nitric oxide: A theoretical research.Frontiers in chemistry · 2022Article
- Activatable NIR-II organic fluorescent probes for bioimaging.Theranostics · 2022Review
- A near-infrared fluorescence probe for imaging of pantetheinase in cells and miceChemical science · 2020Article
- Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications.Chemical science · 2020Review
- A Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide.Scientific reports · 2019Article
- Visualization of methylglyoxal in living cells and diabetic mice model with a 1,8-naphthalimide-based two-photon fluorescent probe.Chemical science · 2018Article
- Theoretical Design of a Two-Photon Fluorescent Probe for Nitric Oxide with Enhanced Emission Induced by Photoninduced Electron Transfer.Sensors (Basel, Switzerland) · 2018Article
- A Ratiometric Acoustogenic Probe for in Vivo Imaging of Endogenous Nitric Oxide.Journal of the American Chemical Society · 2018Article
- Addressing the autofluorescence issue in deep tissue imaging by two-photon microscopy: the significance of far-red emitting dyes.Chemical science · 2017Article
- Ru(II)-Catalyzed Regiospecific C-H/O-H Oxidative Annulation to Access Isochromeno[8,1-ACS omega · 2017Article
- AnChemical science · 2017Article
- Nitroxidative Signaling Mechanisms in Pathological Pain.Trends in neurosciences · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a pivotal signalling molecule involved in various physiological and pathological processes, nitric oxide (NO) has motivated increasing interest in the last few decades. Although a considerable number of fluorescent probes have been developed for NO imaging, the
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.