Evidence map›Paper›PMID 30155162›Full record

ArticleChemical science2016

Multilayered semiconducting polymer nanoparticles with enhanced NIR fluorescence for molecular imaging in cells, zebrafish and mice.

Houjuan Zhu, Yuan Fang, Xu Zhen, Na Wei, Yu Gao, Kathy Qian Luo, Chenjie Xu, Hongwei Duan, Dan Ding, Peng Chen and 1 more

Abstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Ultrabright NIR-II Nanoprobes forACS nanoscience Au · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Fluorescent Polymer Dots for Tracking SKOVMolecular imaging and biology · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Optically Active Nanomaterials for Bioimaging and Targeted Therapy.Frontiers in bioengineering and biotechnology · 2019
    Review
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Houjuan ZhuSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Yuan FangState Key Laboratory of Medicinal Chemical Biology , Key Laboratory of Bioactive Materials , Ministry of Education , College of Life Sciences , Nankai University , China . Email: dingd@nankai.edu.cn.
Xu ZhenSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Na WeiSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Yu GaoSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Kathy Qian LuoFaculty of Health Sciences , University of Macau , Avenida da Universidade , Taipa , Macau , China.
Chenjie XuSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Hongwei DuanSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Dan DingState Key Laboratory of Medicinal Chemical Biology , Key Laboratory of Bioactive Materials , Ministry of Education , College of Life Sciences , Nankai University , China . Email: dingd@nankai.edu.cn.
Peng ChenSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.
Kanyi PuSchool of Chemical and Biomedical Engineering , Nanyang Technological University , Singapore 637457 . Email: chenpeng@ntu.edu.sg ; Email: kypu@ntu.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although organic semiconducting polymer nanoparticles (SPNs) have emerged as an important category of optical imaging agents, their application in molecular imaging is still in its infancy and faces many challenges. We herein report a straightforward one-pot synthetic approach to construct multilayered near-infrared (NIR) fluorescent SPNs with enhanced fluorescence and optimized biodistribution for

Identifiers

PMID30155162
PMCPMC6020125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.