ArticleChemical science2016
Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Iodine(III)-Mediated Oxidation of Anilines to Construct Dibenzazepines.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Chemical insights into the synthetic chemistry of five-membered saturated heterocycles-a transition metal-catalyzed approach.Frontiers in chemistry · 2023Review
- Copper-catalyzed oxidative dehydrogenative dearomatization of indole derivatives: A new strategy to construct spirocyclic indolenines.iScience · 2022Article
- Iridium-catalyzed enantioselective alkynylation and kinetic resolution of alkyl allylic alcohols.Chemical science · 2022Article
- Advances in Catalytic Asymmetric Dearomatization.ACS central science · 2021Review
- Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis.Journal of the American Chemical Society · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
An Ir-catalyzed asymmetric synthesis of five-membered aza-spiroindolenines is achieved. Based on the detailed investigation of the reaction patterns of the aryl iminium migration, a one-pot asymmetric allylic dearomatization/migration sequence from racemic indole derivatives is realized, affording enantioenriched Pictet-Spengler-type products bearing an additional allylic stereogenic center adjacent to the C3 position of the indole core.
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Registered trials
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