ArticleChemical science2016
Single near-infrared fluorescent probe with high- and low-sensitivity sites for sensing different concentration ranges of biological thiols with distinct modes of fluorescence signals.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 144 citations in OpenAlex.
- A Water-Soluble Small-Molecule Fluorescent Probe for Selective Imaging of Colorectal Cancer with High Biosafety.Journal of fluorescence · 2025Article
- Activatable fluorescent probes for imaging and diagnosis of rheumatoid arthritis.Military Medical Research · 2023Review
- Enlightening the Path to Protein Engineering: Chemoselective Turn-On Probes for High-Throughput Screening of Enzymatic Activity.Chemical reviews · 2023Review
- Near-Infrared Probes for Biothiols (Cysteine, Homocysteine, and Glutathione): A Comprehensive Review.ACS omega · 2023Review
- An insight into theAsian journal of pharmaceutical sciences · 2021Review
- A rapid "on-off-on" mitochondria-targeted phosphorescent probe for selective and consecutive detection of CuRSC advances · 2021Article
- Fluorescent small organic probes for biosensing.Chemical science · 2021Review
- A new pentacyclic pyrylium fluorescent probe that responds to pH imbalance during apoptosis.Chemical science · 2020Article
- Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe.Chemical science · 2019Article
- Lysosome-Targeted Single Fluorescence Probe for Two-Channel Imaging Intracellular SO₂ and Biothiols.Molecules (Basel, Switzerland) · 2019Article
- Fluorescent probes guided by a new practical performance regulation strategy to monitor glutathione in living systems.Chemical science · 2018Article
- Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging.Chemical science · 2018Review
- Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.Angewandte Chemie (International ed. in English) · 2017Review
- A ratiometric fluorescent probe for imaging and quantifying anti-apoptotic effects of GSH under temperature stress.Chemical science · 2017Article
- pH-Dependent Fluorescent Probe That Can Be Tuned for Cysteine or Homocysteine.Organic letters · 2017Article
- A novel approach to study the structure-property relationships and applications in living systems of modular Cu(2+) fluorescent probes.Scientific reports · 2016Article
- NIR in, far-red out: developing a two-photon fluorescent probe for tracking nitric oxide in deep tissue.Chemical science · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a unique approach for the development of an interesting type of the fluorescent probes, which can show different modes of fluorescence signals to distinct concentration ranges of a target of interest. The key points for the design of the new type of the fluorescent probes include the judicious selection of the dye platforms and the corresponding high- and low-sensitivity sites. It is known that the normal concentrations of biological thiols have significant biological functions. However, up- or down-regulated concentrations of thiols may induce several diseases. Therefore, it is highly important to monitor the changes of thiol concentrations in living systems. Based on the proposed strategy, we engineer the novel NIR fluorescent probe,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.