Evidence map›Paper›PMID 30154796›Full record

ArticleFrontiers in immunology2018

Luigi Lembo-Fazio, Jean-Marc Billod, Flaviana Di Lorenzo, Ida Paciello, Mateusz Pallach, Sara Vaz-Francisco, Aurora Holgado, Rudi Beyaert, Manuel Fresno, Atsushi Shimoyama and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. PairingACS central science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 5 countries.

Luigi Lembo-FazioDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza-Università di Roma, Rome, Italy.
Jean-Marc BillodDepartment of Structural and Chemical Biology, Centro de Investigaciones Biológicas, CIB-CSIC, Madrid, Spain.
Flaviana Di LorenzoDipartimento di Scienze Chimiche, Complesso Universitario Monte Sant'Angelo, Università di Napoli Federico II, Naples, Italy.
Ida PacielloDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza-Università di Roma, Rome, Italy.
Mateusz PallachDipartimento di Scienze Chimiche, Complesso Universitario Monte Sant'Angelo, Università di Napoli Federico II, Naples, Italy.
Sara Vaz-FranciscoDiomune SL, Parque Científico de Madrid, Madrid, Spain.
Aurora HolgadoCenter for Inflammation Research, Unit of Molecular Signal Transduction in Inflammation, VIB, Ghent, Belgium.
Rudi BeyaertCenter for Inflammation Research, Unit of Molecular Signal Transduction in Inflammation, VIB, Ghent, Belgium.
Manuel FresnoDiomune SL, Parque Científico de Madrid, Madrid, Spain.
Atsushi ShimoyamaDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Rosa LanzettaDipartimento di Scienze Chimiche, Complesso Universitario Monte Sant'Angelo, Università di Napoli Federico II, Naples, Italy.
Koichi FukaseDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan.
Djamel GullyIRD, Laboratoire des Symbioses Tropicales et Méditerranéennes (LSTM), UMR IRD/SupAgro/INRA/UM2/CIRAD, TA-A82/J - Campus de Baillarguet, Montpellier, France.
Eric GiraudIRD, Laboratoire des Symbioses Tropicales et Méditerranéennes (LSTM), UMR IRD/SupAgro/INRA/UM2/CIRAD, TA-A82/J - Campus de Baillarguet, Montpellier, France.
Sonsoles Martín-SantamaríaDepartment of Structural and Chemical Biology, Centro de Investigaciones Biológicas, CIB-CSIC, Madrid, Spain.
Maria-Lina BernardiniDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza-Università di Roma, Rome, Italy.
Alba SilipoDipartimento di Scienze Chimiche, Complesso Universitario Monte Sant'Angelo, Università di Napoli Federico II, Naples, Italy.
University of Naples Federico II · ITCentro de Investigaciones Biológicas Margarita Salas · ESOsaka University · JPSapienza University of Rome · ITUnidades Centrales Científico-Técnicas · ESCentre de Coopération Internationale en Recherche Agronomique pour le Développement · FRGhent University · BEInstitut de Recherche pour le Développement · FRIstituto Pasteur · ITVIB-UGent Center for Inflammation Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharides (LPS) are potent activator of the innate immune response through the binding to the myeloid differentiation protein-2 (MD-2)/toll-like receptor 4 (TLR4) receptor complexes. Although a variety of LPSs have been characterized so far, a detailed molecular description of the structure-activity relationship of the lipid A part has yet to be clarified. Photosynthetic

Indexed as

AnimalsBradyrhizobiumCell LineCytokinesFemaleHumansImmunity, InnateLeukocytes, MononuclearLipid ALymphocyte Antigen 96MiceMice, Inbred C57BLModels, MolecularMolecular ConformationProtein BindingStructure-Activity RelationshipCytokinesLipid ALymphocyte Antigen 96Toll-Like Receptor 4Bradyrhizobium lipid Ainflammatory cytokinesinnate immunitylipopolysaccharidemolecular modelingmyeloid differentiation protein-2/toll-like receptor 4

Identifiers

PMID30154796
PMCPMC6102379
OpenAlexW2885082572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.