Evidence map›Paper›PMID 30154773›Full record

ArticleFrontiers in microbiology2018

The Energy-Coupling Factor Transporter Module EcfAA'T, a Novel Candidate for the Genetic Basis of Fatty Acid-Auxotrophic Small-Colony Variants of

Nina Schleimer, Ursula Kaspar, Mike Drescher, Jochen Seggewiß, Christof von Eiff, Richard A Proctor, Georg Peters, André Kriegeskorte, Karsten Becker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. An energy coupling factor transporter ofbioRxiv : the preprint server for biology · 2024
    Article
  3. Review
  4. Antibiotics (Basel, Switzerland) · 2023
    Article
  5. Subpopulations in Strains ofAntibiotics (Basel, Switzerland) · 2023
    Review
  6. Triclosan-resistant small-colony variants ofMicrobiology (Reading, England) · 2023
    Article
  7. FunctionalJournal of bacteriology · 2022
    Article
  8. The road to success of coagulase-negative staphylococci: clinical significance of small colony variants and their pathogenic role in persistent infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  9. Article
  10. Persistence ofFrontiers in microbiology · 2020
    Review
  11. Novel Research Models forFrontiers in microbiology · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nina SchleimerInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Ursula KasparInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Mike DrescherInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Jochen SeggewißInstitute of Human Genetics, University Hospital Münster, Münster, Germany.
Christof von EiffInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Richard A ProctorDepartments of Medical Microbiology/Immunology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Georg PetersInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
André KriegeskorteInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
Karsten BeckerInstitute of Medical Microbiology, University Hospital Münster, Münster, Germany.
University Hospital Münster · DEUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcal small-colony variants (SCVs) are invasive and persistent due to their ability to thrive intracellularly and to evade the host immune response. Thus, the course of infections due to this phenotype is often chronic, relapsing, and therapy-refractory. In order to improve treatment of patients suffering from SCV-associated infections, it is of major interest to understand triggers for the development of this phenotype, in particular for strains naturally occurring in clinical settings. Within this study, we comprehensively characterized two different

Indexed as

energy-coupling factor transporter (EcfAA’T)fatty acid-auxotrophyphenotype switchsmall-colony variants (SCVs)Staphylococcus aureuswhole-genome sequencing

Identifiers

PMID30154773
PMCPMC6102330
OpenAlexW2885909611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.