Evidence map›Paper›PMID 30154717›Full record

ArticleFrontiers in pharmacology2018

MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With

Rossella Salemi, Luca Falzone, Gabriele Madonna, Jerry Polesel, Diana Cinà, Domenico Mallardo, Paolo A Ascierto, Massimo Libra, Saverio Candido

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Predictive Performance of Serum S100BFrontiers in oncology · 2021
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  17. Chronic Pesticide Exposure in Farm Workers Is Associated with the Epigenetic Modulation of hsa-miR-199a-5p.International journal of environmental research and public health · 2022
    Article
  18. BRAF Inhibitors in Melanoma Management: When Friends Become Foes.The Journal of investigative dermatology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rossella SalemiDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Luca FalzoneDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Gabriele MadonnaUnit of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori "Fondazione G. Pascale", Naples, Italy.
Jerry PoleselUnit of Cancer Epidemiology, Aviano National Cancer Institute, IRCCS, Aviano, Italy.
Diana CinàClinical Pathology Unit, Garibaldi Hospital, Catania, Italy.
Domenico MallardoUnit of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori "Fondazione G. Pascale", Naples, Italy.
Paolo A AsciertoUnit of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori "Fondazione G. Pascale", Naples, Italy.
Massimo LibraDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Saverio CandidoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
University of Catania · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITCentro di Riferimento Oncologico · ITOspedale Garibaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

biomarkerBRAFV600Ecirculating-free DNAdroplet digital PCRliquid biopsyMMP-9

Identifiers

PMID30154717
PMCPMC6102751
OpenAlexW2885476476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.