Evidence map›Paper›PMID 30154630›Full record

ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2018

Risk and Benefits of Statins in Glucose Control Management of Type II Diabetes.

Anthony Paulo Sunjaya, Angela Felicia Sunjaya, Samuel Halim, Frans Ferdinal

Abstract readReview
In one paragraph

Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anthony Paulo SunjayaFaculty of Medicine, Tarumanagara University, Jakarta, Indonesia.
Angela Felicia SunjayaFaculty of Medicine, Tarumanagara University, Jakarta, Indonesia.
Samuel HalimDepartment of Internal Medicine, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia.
Frans FerdinalDepartment of Biochemistry, Faculty of Medicine, Tarumanagara University, Jakarta, Indonesia.
Tarumanagara University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide statins are considered to be the first-line pharmacological treatment for dyslipidemia and reducing the risk of coronary heart disease. However, recently various studies have shown its adverse effect on glucose control among diabetic patients and the U.S. Food and Drug Administration have revised statin drug labels to include information that increases in fasting serum glucose and glycated hemoglobin levels have been reported. This systematic review objective is to evaluate the risks and benefits of statins in glucose control management of type 2 diabetes patients based on the 44 published journal articles included and obtained through MEDLINE full text, PubMed, Science Direct, Pro Quest, SAGE, Taylor and Francis Online, Google Scholar, High Wire, and Elsevier Clinical Key. Statins were found to affect glucose control through several ways, namely, by affecting insulin production and secretion by β-pancreatic cells, insulin resistance, insulin uptake by the muscles and adipocytes and production of adipokines. Current evidence available shows that most of the statins give unfavorable side effects with regards to glucose control among diabetic patients. A dose-dependent and time-dependent effect was also observed in some statins which may be present among other statins as well.

Indexed as

diabetesglucose controlhypercholesterolemiainsulin resistanceinsulin secretioninsulin sensitivitystatins

Identifiers

PMID30154630
PMCPMC6103774
OpenAlexW2338957011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.