Evidence map›Paper›PMID 30154548›Full record

ArticleNature cell biology2018

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Jun Liu, Mark A Eckert, Bryan T Harada, Song-Mei Liu, Zhike Lu, Kangkang Yu, Samantha M Tienda, Agnieszka Chryplewicz, Allen C Zhu, Ying Yang and 10 more

Open access · greenAbstract read
In one paragraph

Article in Nature cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 520 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
520citing papers in PubMed, 1 pooled it
41.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

520 citing papers in PubMed, 1 synthesis or guideline pooled it, 864 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  6. Article
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  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. NNature reviews. Cancer · 2026
    Review
  14. Review
  15. m6A modification and its clinical applications in gynaecological cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

460 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Jun Liu *Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Mark A Eckert *Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-3166-3440
Bryan T Harada *Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-9683-782X
Song-Mei Liu *Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhike LuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Kangkang YuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Samantha M TiendaDepartment of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL, USA.
Agnieszka ChryplewiczDepartment of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL, USA.
Allen C ZhuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Ying YangCenter for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jing-Tao HuangCenter for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shao-Min ChenCenter for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhi-Gao XuDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiao-Hua LengHubei Key Laboratory of Tumor Biological Behaviors & Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xue-Chen YuDepartment of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jie CaoMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.
Zezhou ZhangMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.
Jianzhao LiuMOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-9465-6075
Ernst LengyelDepartment of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL, USA. elengyel@uchicago.edu.ORCID http://orcid.org/0000-0001-8624-1507
Chuan HeDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424
Howard Hughes Medical Institute · USWuhan University · CNUniversity of Chicago · USZhejiang University · CN

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Regulation of Adhesion and Proteolysis in Ovarian CancerR01CA111882 · NCI · UNIVERSITY OF CHICAGO · PI LENGYEL, ERNST · 2006 to 2016
$2.8M
Base-resolution sequencing of m6A in RNAR01HG008688 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2015 to 2017
$1.3M
The Effects of ERK2-Induced Phosphorylation of METTL3 on N6-methyladenosine (m6A) mRNA Methylation in MelanomaF30CA247175 · NCI · UNIVERSITY OF CHICAGO · PI ZHU, ALLEN C · 2020 to 2023
$192k
The role of mRNA methylation in the progression of endometrial cancerF32CA221007 · NCI · UNIVERSITY OF CHICAGO · PI HARADA, BRYAN TSUTOMU · 2017 to 2019
$179k
NCI NIH HHS F30 CA247175NCI NIH HHS F32 CA221007NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA111882NHGRI NIH HHS R01 HG008688NHGRI NIH HHS RM1 HG008935
6 · The paper itself

Abstract

N

Indexed as

CarcinogenesisCell ProliferationRNA Processing, Post-TranscriptionalAdenosineAnimalsCell Line, TumorEndometrial NeoplasmsFemaleGene Expression Regulation, NeoplasticHumansMechanistic Target of Rapamycin Complex 2MethylationMethyltransferasesMice, NudeMutationPhosphoprotein PhosphatasesAdenosineMechanistic Target of Rapamycin Complex 2MethyltransferasesMETTL14 protein, humanMETTL3 protein, humanN-methyladenosinePHLPP2 protein, humanPhosphoprotein PhosphatasesProto-Oncogene Proteins c-aktRNA, MessengerRNA, Neoplasm

Identifiers

PMID30154548
PMCPMC6245953
OpenAlexW2886253007

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.