Evidence map›Paper›PMID 30154520›Full record

ArticleScientific reports2018

Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation.

Andrey A Yurchenko, Hans D Daetwyler, Nikolay Yudin, Robert D Schnabel, Christy J Vander Jagt, Vladimir Soloshenko, Bulat Lhasaranov, Ruslan Popov, Jeremy F Taylor, Denis M Larkin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 128 citations in OpenAlex.

  1. Review
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  3. Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
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  19. Analysis of Runs of Homozygosity in Aberdeen Angus Cattle.Animals : an open access journal from MDPI · 2024
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Andrey A YurchenkoThe Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), 630090, Novosibirsk, Russia.ORCID 0000-0002-2239-6902
Hans D DaetwylerAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, 3083, Victoria, Australia.
Nikolay YudinThe Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), 630090, Novosibirsk, Russia.
Robert D SchnabelDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211-5300, USA.ORCID 0000-0001-5018-7641
Christy J Vander JagtAgriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, 3083, Victoria, Australia.
Vladimir SoloshenkoSiberian Research Institute of Animal Husbandry, 630501, Krasnoobsk, Russia.
Bulat LhasaranovShuluuma IAPC, Kizhinga, 671450, Buryatia, Russia.
Ruslan PopovYakutian Research Institute of Agriculture, 677001, Yakutsk, Russia.
Jeremy F TaylorDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211-5300, USA.ORCID 0000-0002-6997-7245
Denis M LarkinThe Federal Research Center Institute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences (ICG SB RAS), 630090, Novosibirsk, Russia. dmlarkin@gmail.com.
Institute of Cytology and Genetics · RUUniversity of Missouri · USAgriculture Victoria · AULa Trobe University · AUSiberian Research Institute of Animal Husbandry · RUUniversity of London · GBYakut Scientific Research Institute of Agriculture · RU

Funding

Russian Science Foundation (RSF) 16-14-00090
6 · The paper itself

Abstract

Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments. These adaptations are a valuable source of genetic material for efforts to improve commercial breeds. As a step toward this goal we identified candidate regions to be under selection in genomes of nine Russian native cattle breeds adapted to survive in harsh climates. After comparing our data to other breeds of European and Asian origins we found known and novel candidate genes that could potentially be related to domestication, economically important traits and environmental adaptations in cattle. The Russian cattle breed genomes contained regions under putative selection with genes that may be related to adaptations to harsh environments (e.g., AQP5, RAD50, and RETREG1). We found genomic signatures of selective sweeps near key genes related to economically important traits, such as the milk production (e.g., DGAT1, ABCG2), growth (e.g., XKR4), and reproduction (e.g., CSF2). Our data point to candidate genes which should be included in future studies attempting to identify genes to improve the extant breeds and facilitate generation of commercial breeds that fit better into the environments of Russia and other countries with similar climates.

Indexed as

GenomeQuantitative Trait, HeritableSelective BreedingAcclimatizationAnimalsCattleFemaleMaleRussia

Identifiers

PMID30154520
PMCPMC6113280
OpenAlexW2888347958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.