Trial reportScientific reports2018
Risk of Hyperlipidemia in Women with Hysterectomy-A Retrospective Cohort Study in Taiwan.
Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Hysterectomy accelerates sarcopenia risk in US women and mouse models.Frontiers in endocrinology · 2026Article
- Article
- Association of hysterectomy with nonalcoholic fatty liver disease among US women.Lipids in health and disease · 2024Article
- Phytochemical components analysis and hypolipidemic effect on hyperlipidemia mice of the aerial parts fromFrontiers in nutrition · 2024Article
- Prevalence and determinants of hysterectomy in India.Scientific reports · 2023Observational
- Hysterectomy With and Without Oophorectomy, Tubal Ligation, and Risk of Cardiovascular Disease in the Nurses' Health Study II.Journal of women's health (2002) · 2023Article
- An audit of hysterectomy in a teaching hospital in India: Story of a decade.Journal of the Chinese Medical Association : JCMA · 2023Article
- The Role of MicroRNAs in Hyperlipidemia: From Pathogenesis to Therapeutical Application.Mediators of inflammation · 2022Review
- What We Know about the Long-Term Risks of Hysterectomy for Benign Indication-A Systematic Review.Journal of clinical medicine · 2021Review
- Association of laparoscopy and laparotomy with adverse fetal outcomes: a retrospective population-based case-control study.Surgical endoscopy · 2021Article
- Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Article
- Increased risk of knee osteoarthritis in patients using oral N-acetylcysteine: a nationwide cohort study.BMC musculoskeletal disorders · 2020Article
- Aspirin associated with a decreased incidence of uterine cancer: A retrospective population-based cohort study.Medicine · 2020Observational
- Outcomes of laparoscopic hysteropexy and supracervical hysterectomy plus cervicopexy: A retrospective study.Tzu chi medical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hysterectomy has been associated with metabolic change and cardiovascular risk for women after removing the uterus, but inconclusive. This large retrospective cohort study evaluated the hyperlipidemia risk for women with a hysterectomy and/or oophorectomy. From claims data of one million people in the National Health Insurance (NHI) database of Taiwan, we established a cohort consisting of 5887 women newly received a surgery of hysterectomy from 2000-2013, 563 women had a hysterectomy and a oophorectomy, and 556 women had a oophorectomy. From the claims data, 28024 women without any of the surgeries were identified to form the comparison cohort, frequency matched by birth year and surgery year of the women with hysterectomy. By the end of 2013, the incidence of hyperlipidemia was 1.3 times greater in women with a hysterectomy than in comparison women (3.43 vs. 2.65 per 100 person-years), with an adjusted hazard ratio (aHR) of 1.27 (95% CI = 1.19-1.35) for hysterectomy women after controlling for age, oophorectomy, hormone therapy and comorbidities. The incidence of hyperlipidemia increased to 4.93 per 100 person-years in women with both a hysterectomy and an oophorectomy. The relative risk of hyperlipidemia was higher for young women than the elderly women with the surgery. Women with comorbidity of obesity, hypertension or diabetes had a higher incidence of hyperlipidemia. In conclusion, the risk of developing hyperlipidemia could be elevated for women who had a hysterectomy and/or an oophorectomy. Women with hysterectomy should routinely monitor their metabolic status, particularly for young women and those with comorbidity of metabolic symptoms.
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