Evidence map›Paper›PMID 30154362›Full record

ArticleVaccines2018

β-Defensins Coordinate In Vivo to Inhibit Bacterial Infections of the Trachea.

Lisa Kathleen Ryan, Jichuan Wu, Kyell Schwartz, Sunghan Yim, Gill Diamond

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Frontiers in cellular and infection microbiology · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lisa Kathleen RyanThe Public Health Research Institute Center, Rutgers New Jersey Medical School, Newark, NJ 07103, USA. Lisa.Ryan@medicine.ufl.edu.ORCID 0000-0001-6422-7720
Jichuan WuDepartment of Oral Biology, Rutgers New Jersey Dental School, Newark, NJ 07103, USA. jichuan.wu@temple.edu.
Kyell SchwartzDepartment of Oral Biology, Rutgers New Jersey Dental School, Newark, NJ 07103, USA. kyellschwartz426@gmail.com.
Sunghan YimDepartment of Oral Biology, Rutgers New Jersey Dental School, Newark, NJ 07103, USA. yimsu75@gmail.com.
Gill DiamondDepartment of Oral Biology, Rutgers New Jersey Dental School, Newark, NJ 07103, USA. gdiamond@dental.ufl.edu.
Rutgers, The State University of New Jersey · US

Funding

Bacteria-host cell interactions in periodontal diseaseR01DE014897 · NIDCR · UNIV OF MED/DENT OF NJ-NJ DENTAL SCHOOL · PI DIAMOND, GILL · 2002 to 2005
$1.6M
Host-Pathogen Interactions in the Mammalian AirwayR01HL067871 · NHLBI · UNIV OF MED/DENT OF NJ-NJ DENTAL SCHOOL · PI DIAMOND, GILL · 2003 to 2006
$1.2M
Human Beta-Defensin-1 in HSV-1 Innate ImmunityR21AI072245 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RYAN, LISA KATHLEEN · 2007 to 2010
$434k
Inhibition of lung defense by air pollutant particulatesR03ES016851 · NIEHS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RYAN, LISA KATHLEEN · 2009 to 2010
$173k
National Institutes of Health R01DE14897, R01HL67871, AI26806S1, R21AI072245, R03ES016851NHLBI NIH HHS R01 HL067871NIAID NIH HHS R21 AI072245NIDCR NIH HHS R01 DE014897NIEHS NIH HHS R03 ES016851
6 · The paper itself

Abstract

β-defensins are predicted to play an important role in innate immunity against bacterial infections in the airway. We previously observed that a type III-secretion product of

Indexed as

Bordetella bronchisepticaepithelial cellsinnate immunityβ-defensins

Identifiers

PMID30154362
PMCPMC6161282
OpenAlexW2889513951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.