Evidence map›Paper›PMID 30154341›Full record

ReviewChildren (Basel, Switzerland)2018

High-Risk Neuroblastoma Treatment Review.

Valeria Smith, Jennifer Foster

Registry-linked trialAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05303727 (Clinical Research of Allogeneic Hematopoietic Stem Cell Transplantation for Treatment of Children With Stage 4/M Neuroblastoma), which is not on this map. Cited by 138 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05303727 phase2not yet recruitingnot on this mapstarted 2022, after this paper: background citation

Clinical Research of Allogeneic Hematopoietic Stem Cell Transplantation for Treatment of Children With Stage 4/M Neuroblastoma: A Prospective, Single-arm, Phase II, Multi-center Trial

TypeinterventionalSponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityRan2022 to 2027Enrolled64ConditionsNeuroblastomaArmsAnti Thymocyte Globulin, Fludarabine, Cyclophosphamide injection, Topotecan, Melphalan
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Retinoic acid in health and disease.Signal transduction and targeted therapy · 2026
    Review
  4. Integration of Bulk RNA Sequencing and Single-Cell Sequencing to Identify Prognostic Genes Associated With MCDRGs in Neuroblastoma.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Valeria SmithBaylor College of Medicine Department of Pediatrics, Texas Children's Cancer and Hematology Center, Houston, TX 77030, USA. vs134101@bcm.edu.
Jennifer FosterBaylor College of Medicine Department of Pediatrics, Texas Children's Cancer and Hematology Center, Houston, TX 77030, USA. jhfoster@txch.org.ORCID 0000-0002-2126-9768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial solid tumor in children. One subset, high-risk neuroblastoma, is very difficult to treat and requires multi-modal therapy. Intensification of therapy has vastly improved survival rates, and research is focused on novel treatments to further improve survival rates. The current treatment schema is divided into three stages-induction, consolidation, and maintenance. This review serves as an overview of the current treatment for high-risk neuroblastoma and a glimpse at current research for future therapy.

Indexed as

diagnosishigh-risk neuroblastomaneuroblastomatreatment

Identifiers

PMID30154341
PMCPMC6162495

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.